GATE Syllabus for Biotechnology

2010 April 20

This post will be updated if any changes are announced by the GATE 2011 organizing institute. This GATE syllabus is a part of GATE 2011 Preparation: A complete Guide. I would also recommend you to refer A set of ‘Must Read’ articles for M.Tech aspirants which I wrote over a year answering questions of M.Tech aspirants.
Also you might be interested in Number of Students appeared in GATE 2010 and GATE 2010 Qualifying marks. Another good informative post is about Highest marks in GATE 2010.

GATE 2011 Syllabus for Biotechnology is as follows:

General Aptitude (GA)

Verbal Ability: English grammar, sentence completion, verbal analogies, word groups, instructions, critical reasoning and verbal deduction.

Numerical Ability: Numerical computation, numerical estimation, numerical reasoning and data interpretation.

Engineering Mathematics

Linear Algebra: Matrices and determinants, Systems of linear equations, Eigen values and Eigen vectors.

Calculus: Limit, continuity and differentiability, Partial derivatives, Maxima and minima, Sequences and series, Test for convergence, Fourier Series.

Differential Equations: Linear and nonlinear first order ODEs, higher order ODEs with constant coefficients, Cauchy’s and Euler’s equations, Laplace transforms, PDE- Laplace, heat and wave equations.

Probability and Statistics: Mean, median, mode and standard deviation, Random variables, Poisson, normal and binomial distributions, Correlation and regression analysis.

Numerical Methods: Solution of linear and nonlinear algebraic equations, Integration of trapezoidal and Simpson’s rule, Single and multistep methods for differential equations.

Biotechnology

Microbiology: Prokaryotic and eukaryotic cell structure; Microbial nutrition, growth and control; Microbial metabolism (aerobic and anaerobic respiration, photosynthesis); Nitrogen fixation; Chemical basis of mutations and mutagens; Microbial genetics (plasmids, transformation, transduction, conjugation); Microbial diversity and characteristic features; Viruses.

Biochemistry: Biomolecules and their conformation; Ramachandran map; Weak inter-molecular interactions in biomacromolecules; Chemical and functional nature of enzymes; Kinetics of single substrate and bi-substrate enzyme catalyzed reactions; Bioenergetics; Metabolism (Glycolysis, TCA and Oxidative phosphorylation); Membrane transport and pumps; Cell cycle and cell growth control; Cell signaling and signal transduction; Biochemical and biophysical techniques for macromolecular analysis.

Molecular Biology and Genetics: Molecular structure of genes and chromosomes; DNA replication and control; Transcription and its control; Translational processes; Regulatory controls in prokaryotes and eukaryotes; Mendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extrachromosomal inheritance; Chromosomal variation; Population genetics; Transposable elements, Molecular basis of genetic diseases and applications.

Process Biotechnology: Bioprocess technology for the production of cell biomass and primary/secondary metabolites, such as baker’s yeast, ethanol, citric acid, amino acids, exo-polysacharides, antibiotics and pigments etc.; Microbial production, purification and bioprocess application(s) of industrial enzymes; Production and purification of recombinant proteins on a large scale; Chromatographic and membrane based bioseparation methods; Immobilization of enzymes and cells and their application for bioconversion processes. Aerobic and anaerobic biological processes for stabilization of solid / liquid wastes; Bioremediation.

Bioprocess Engineering: Kinetics of microbial growth, substrate utilization and product formation; Simple structured models; Sterilization of air and media; Batch, fed-batch and continuous processes; Aeration and agitation; Mass transfer in bioreactors; Rheology of fermentation fluids; Scale-up concepts; Design of fermentation media; Various types of microbial and enzyme reactors; Instrumentation in bioreactors.

Plant and Animal Biotechnology: Special features and organization of plant cells; Totipotency; Regeneration of plants; Plant products of industrial importance; Biochemistry of major metabolic pathways and products; Autotrophic and heterotrophic growth; Plant growth regulators and elicitors; Cell suspension culture development: methodology, kinetics of growth and production formation, nutrient optimization; Production of secondary metabolites by plant suspension cultures; Hairy root cultures and their cultivation. Techniques in raising transgencies.

Characteristics of animal cells: Metabolism, regulation and nutritional requirements for mass cultivation of animal cell cultures; Kinetics of cell growth and product formation and effect of shear force; Product and substrate transport; Micro & macro-carrier culture; Hybridoma technology; Live stock improvement; Cloning in animals; Genetic engineering in animal cell culture; Animal cell preservation.

Immunology: The origin of immunology; Inherent immunity; Humoral and cell mediated immunity; Primary and secondary lymphoid organ; Antigen; B and T cells and Macrophages; Major histocompatibility complex (MHC); Antigen processing and presentation; Synthesis of antibody and secretion; Molecular basis of antibody diversity; Polyclonal and monoclonal antibody; Complement; Antigen-antibody reaction; Regulation of immune response; Immune tolerance; Hyper sensitivity; Autoimmunity; Graft versus host reaction.

Recombinant DNA Technology: Restriction and modification enzymes; Vectors: plasmid, bacteriophage and other viral vectors, cosmids, Ti plasmid, yeast artificial chromosome; cDNA and genomic DNA library; Gene isolation; Gene cloning; Expression of cloned gene; Transposons and gene targeting; DNA labeling; DNA sequencing; Polymerase chain reactions; DNA fingerprinting; Southern and northern blotting; In-situ hybridization; RAPD; RFLP; Site-directed mutagenesis; Gene transfer technologies; Gene therapy.

Bioinformatics: Major bioinformatics resources (NCBI, EBI, ExPASy); Sequence and structure databases; Sequence analysis (biomolecular sequence file formats, scoring matrices, sequence alignment, phylogeny); Genomics and Proteomics (Large scale genome sequencing strategies; Comparative genomics; Understanding DNA microarrays and protein arrays); Molecular modeling and simulations (basic concepts including concept of force fields).

Related posts:

  1. GATE Syllabus for Botany-XL
  2. GATE Syllabus for Zoology-XL
  3. GATE Syllabus for Microbiology-XL
  4. GATE Syllabus for Biochemistry-XL
  5. GATE Syllabus for Food Technology-XE

from → GATE Exam

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  1. shailesh pratap Permalink

    sir …. i am pursuing b.tech in biotechnology from nit durgapur.
    sir …. will u plz tell me that, can i do m.tech from chemical ?
    if it is so then what will be the syllabus for ‘GATE’.
    will the syllabus is , what i studying chemical subjects in biotech or it is totally come from chemical engineering ????
    plz reply sir as soon as possible…. thanks..

  2. RATAN SINGH Permalink

    hi sir,

    please send me previous examination papers for all biotech subjects….

  3. hello sir pls send me study materials and some model test papers of gate

  4. PALLABI Permalink

    PLZZ GIVE ME THE PREVIOUS YEAR GATE QUESTION PAPERS

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  6. neha Permalink

    hello sir ……..
    I am doing B.Sc. biotechnology and little confuse that can i also apply for M.Sc.biotechnology through gate or not .please sir show me the right way.

  7. amandeep kaur Permalink

    please inform me abt phd in biotech

  8. Sir gd mrng……. can u send me previous papers……… pls ……..?

  9. reka Permalink

    throwing model papers is imp r not

  10. ganesh ghule Permalink

    Hello sir….. I WANT TO INFORMATION ABOUT TOP TEN COLLEGES OF M.TECH (BIOTECHNOLOGY)

  11. isha Permalink

    sir i am persuing b.tech in bioinformatics from amity university jaipur will u teel me gate syllabs for m.tech in bioinformatics its same as biotech syllabs

  12. ekta Permalink

    sir can i apply for both biotechnologgy and lifescience in one application forn

  13. deepika Permalink

    sir,

    i want to prepare well for gate 2012,plz help me to crack it.i have completed b.tech biotechnology with good percentage

  14. All Information related to GATE(biotechnology)2012 are available on the website http://www.biofin.net ….rush for your benefits

  15. munmun chowdhury Permalink

    hello sir,
    i am studying btech in biotechnology under wbut..i would like to know that whether i am eligible for doing mtech in chemical engg.if yes, what are the criteria for that and in that case what will be the syllabus for gate?

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