Pre formulation Technology detailed syllabus for Pharmacy (Pharma) for 2021 regulation curriculum has been taken from the Anna Universities official website and presented for the Pharma students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Pharmacy 5th Sem scheme and its subjects, do visit Pharma 5th Sem 2021 regulation scheme. For Professional Elective-II scheme and its subjects refer to Pharma Professional Elective-II syllabus scheme. The detailed syllabus of pre formulation technology is as follows.
Course Objectives:
Download the iStudy App for all syllabus and other updates.
Unit I
INTRODUCTION 8
Preformulation studies of drug substances, proteins and peptides- Fundamental and derived properties in preformulation profiling -Preformulation worksheet.
Unit II
ROLE OF PREFORMULATION IN FORMULATION DEVELOPMENT 8
Preformulation as a support for formulation development- identification of ‘developmental challenges’ during pharmaceutical development – dosage form specific studies.
Unit III
Download the iStudy App for all syllabus and other updates.
Unit IV
SOLUBILIZATION 9
Solubility and solubilization of non-electrolyte- drug solubilization in surfactant systems -use of cosolvents for development of liquid formulations-solid state manipulations including use of metastable solid forms like amorphous state.
Unit V
OPTIMIZATION TECHNIQUES IN PHARMACEUTICAL FORMULATION
AND PROCESSING 12
Introduction- optimization parameters- statistical design-response surface method, contour diagrams, factorial design, partial factorial design, simplex methods, mixture designs, and Box Benken method- applications in pharmaceutical formulation.
Text Books:
- Mark Gibson, Pharmaceutical Preformulation and Formulation, A Practical Guide from Candidate Drug Selection to Commercial Dosage Form,2nd Edition, CRC Press, 2009
- James I. Wells. Ellis Horwood, Pharmaceutical preformulation: The physicochemical properties of drug substances.
- Aulton’s Pharmaceutics, The Design and manufacture of Medicines, Churchill Livingstone Elsevier, 2013.
Reference Books:
Download the iStudy App for all syllabus and other updates.
Course Outcomes:
The students will be able to
- Apprehend the principles of preformulation
- Demonstrate the role of preformulation in Formulation
- Comprehend the strategy of salt selection of drugs
- Understand the solubilisation role in preformulation
- Know the optimization techniques
- Give an overview of preformulation in drug development and formulation
For detailed syllabus of all the other subjects of Pharmacy 5th Sem, visit Pharma 5th Sem subject syllabuses for 2021 regulation.
For all Pharmacy results, visit Anna University Pharma all semester results direct link.