Bioprocess Engineering detailed syllabus for Biotechnology (BioTech) for 2021 regulation curriculum has been taken from the Anna University official website and presented for the BioTech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Biotechnology 6th Sem scheme and its subjects, do visit BioTech 6th Sem 2021 regulation scheme. The detailed syllabus of bioprocess engineering is as follows.
Course Objectives:
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Unit I
CONFIGURATION OF BIOREACTORS 9
Ideal reactors and its characteristics Fed batch cultivation, Cell recycle cultivation, Cell recycle cultivation in waste water treatment, two stage cultivation Packed bed reactor, airlift reactor, introduction to fluidized bed reactor bubble column reactors
Unit II
BIOREACTOR SCALE – UP 9
Regime analysis of bioreactor processes, oxygen mass transfer in bioreactors – microbial oxygen demands; methods for the determination of mass transfer coefficients; mass transfer correlations. Scale up criteria for bioreactors based on oxygen transfer, power consumption and impeller tip speed.
Unit III
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Unit IV
MODELLING AND SIMULATION OF BIOPROCESSES 9
Study of structured models for analysis of various bioprocess – compartmental models, models of cellular energetics and metabolism, single cell models, plasmid replication and plasmid stability model. Dynamic simulation of batch, fed batch, steady and transient culture metabolism.
Unit V
RECOMBINANT CELL CULTIVATION 9
Different host vector system for recombinant cell cultivation strategies and advantages. E.coli, yeast Pichia pastoris/ Saccharomyces cereviseae, Animal cell cultivation, plant cell cultivation, Insect cell cultivation. High cell density cultivation, process strategies, reactor considerations in the above system
Course Outcomes:
Upon completion of this course the student will be able to
- Describe various bioreactor configurations and operation modes.
- Apply the knowledge of bioreactor scale up on the basis of rule of thumbs.
- Define kinetic parameters and apply the bioreactor considerations for immobilized enzymes systems.
- Utilize modelling approaches and simulation concepts for bioprocess estimations.
- Apply bioreactor considerations for the development of recombinant products.
- Explore the engineering concepts of bioreactors.
Text Books:
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Reference Books:
- Anton Moser, “Bioprocess Technology:Kinetics and Reactors”, , Springer Verlag.2012
- James E. Bailey & David F. Ollis, Biochemical Engineering Fundamentals, McGraw Hill,1986
- James M. Lee, Biochemical Engineering, PHI, USA.1992
- Harvey W. Blanch, Douglas S. Clark, Biochemical Engineering, CRC Press,1997
For detailed syllabus of all other subjects of Biotechnology, 2021 regulation curriculum do visit BioTech 6th Sem subject syllabuses for 2021 regulation.
For all Biotechnology results, visit Anna University BioTech all semester results direct link.