PY3412: Physical Pharmaceutics Laboratory syllabus for Pharma 2021 regulation

Physical Pharmaceutics Laboratory detailed syllabus for Pharmacy (Pharma) for 2021 regulation curriculum has been taken from the Anna University official website and presented for the Pharma students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.

For Pharmacy 4th Sem scheme and its subjects, do visit Pharma 4th Sem 2021 regulation scheme. The detailed syllabus of physical pharmaceutics laboratory is as follows.

Course Objectives:

• To practice the determination of fundamental properties of dosage forms of powders and dispersions.
• To study the kinetics and stability aspects of pharmaceuticals.

List of Experiments:

1. Determination of particle size, particle size distribution using various methods of particle size analysis.
2. Determination of surface area of powders.
3. Determination of derived properties of powders like density, porosity, compressibility, angle of repose, etc.
4. Determination of effect of glidant on angle of repose of powder
5. Determination of surface/interfacial tension, HLB value
6. Determination of critical micellar concentration (CMC) of surfactants.
7. Study of rheological properties of various types of systems using different viscometers.
8. Study of different types of colloids and their properties.
9. Preparation of various types of suspensions and determination of their sedimentation parameters.
10. Preparation and stability studies of emulsions.
11. Determination of half-life, rate constant and order of reaction.
12. Preparation of pharmaceutical buffers and determination of buffer capacity.
13. Determination of shelf life of a product based on Arrhenius principle

List of Equipments:

FOR BATCH OF 30 STUDENTS

• Optical Microscope-5nos
• Stage Micrometer-5nos
• Eye piece micrometer-5nos
• Stalagmometer-10nos
• Ostwalds Viscometer-10nos
• Brookfield viscometer-1no.
• Tapped density apparatus-3nos
• Andreason pipette-3nos
• Sieve shaker with sieve sets of different sizes-1no.

Glasswares Required

Pycnometer, Funnel, Beakers, Measuring cylinders,Dessicator,Mortar and pestle

Course Outcomes:

On completion of the course the students will able to

1. Characterize and evaluate the properties of powders by suitable methods
2. Plan and carryout the determination of interfacial property of liquids. .
3. Plan and carryout the determination of viscosity,
4. Plan and carryout the physical stability study of suspension and emulsion dosage forms..
5. Plan and carryout the, preparation of buffer and to determine the buffer capacity and isotonicity of solutions
6. Calculate the rate constant and order of reactions.

Text Books:

1. C.V.S. Subrahmanyam, Physical pharmaceutics-I, 1st Edn., Vallabhprakashan,2019.
2. C.V.S. Subrahmanyam, Physical pharmaceutics – II, 1st Edn., Vallabhprakashan,2019.
3. Manavalan, R. and Ramasamy. C. Physical Pharmaceutics 2nd Ed., Vignesh Publishers, 2015.

Reference Books:

1. Eugene L. Parrott, WitoldSaski, Experimental Pharmaceutics, 4thedn., Burgess Pub. Co., 1977.
2. C.V.S Subrahmanyam&J.ThimmaSetty, Laboratory Manual of Physical Pharmaceutics, 2 nd Ed.,Vallabh Prakashan, 2014.
3. Dr. U. B. Hadkar, Practical Physical Pharmacy & Physical Pharmaceutics, NiraliPrakashan, Pune, 2008.

For detailed syllabus of all other subjects of Pharmacy, 2021 regulation curriculum do visit Pharma 4th Sem subject syllabuses for 2021 regulation.

For all Pharmacy results, visit Anna University Pharma all semester results direct link.