Biopharmaceutics and Pharmacokinetics detailed syllabus for Pharmaceutical Technology (Pharma Tech) for 2019 regulation curriculum has been taken from the Anna Universities official website and presented for the Pharma Tech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Pharmaceutical Technology 7th Sem scheme and its subjects, do visit Pharma Tech 7th Sem 2019 regulation scheme. The detailed syllabus of biopharmaceutics and pharmacokinetics is as follows.
Course Objective:
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Unit I
Drug Absorption and Distribution
Mechanisms of drug absorption through GIT, factors influencing drug absorption through GIT, absorption of drug from Non-per oral extravascular routes, Distribution of drugs, Tissue permeability of drugs, binding of drugs, apparent volume of drug distribution, plasma and tissue protein binding of drugs, factors affecting protein-drug binding. Kinetics of protein binding, Clinical significance of protein binding of drugs.
Unit II
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Unit III
Bioavailability and Bioequivalence
Definition and Objectives of bioavailability, absolute and relative bioavailability, measurement of bioavailability, in-vitro drug dissolution models, in-vitro-in-vivo correlations, bioequivalence studies, methods to enhance the dissolution rates and bioavailability of poorly soluble drugs.
Unit IV
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Unit V
Multiple Dosage Regimens and Nonlinear Pharmacokinetics
Concept, Accumulation, Persistent and elimination factors. Calculation of dosage regimen following repetitive IV and oral administration.Nonlinear Pharmacokinetics – Introduction, factors causing Non-linearity, Michaelis-menton method of estimating pharmacokinetic parameters.
Course Outcome:
For the complete syllabus, results, class timetable, and many other features kindly download the iStudy App
It is a lightweight, easy to use, no images, and no pdfs platform to make students’s lives easier..
Text Books:
- Rosenbaum, S. E. “Basic Pharmacokinetics and Pharmacodynamics: An Integrated Textbook and Computer Simulations”, 2nd Edition, John Wiley and Sons, 2016.
- Brahmankar, D.M. and Jaiswal, S.B. “Biopharmaceutics and Pharmacokinetics: a Treatise”, 3rd Edition, Vallabh Prakashan, 2015.
- Chatwal, G.R. “Biopharmaceutics and Pharmacokinetics”, 2nd Edition, Himalaya Publishing House, 2014.
References:
- Shargel,L and Andrew, B.C. Yu. “Applied Biopharmaceutics and Pharmacokinetics”,7th Edition, The McGraw-Hill Companies, Inc, 2016.
- Gibaldi, M. “Biopharmaceutics and Clinical Pharmacokinetics”, 4th Edition, Pharma Book Syndicate, 2016.
- Jambhekar, S.S. and Philip, J. B. “Basic Pharmacokinetics” 2nd Edition, Pharmaceutical Press,2012.
For detailed syllabus of all other subjects of Pharmaceutical Technology, 2019 regulation curriculum do visit Pharma Tech 7th Sem subject syllabuses for 2019 regulation.
For all Pharmaceutical Technology results, visit Anna University Pharma Tech all semester results direct link.