Physical Pharmaceutics Laboratory detail syllabus for Pharmacy (Pharma), 2017 regulation is taken from Anna University official website and presented for students of Anna University. The details of the course are: course code (PY8311), Category (PC), Contact Periods/week (4), Teaching hours/week (0), Practical Hours/week (0). The total course credits are 4.
For all other pharma 3rd sem syllabus for b.tech 2017 regulation anna univ you can visit Pharma 3rd Sem syllabus for B.Tech 2017 regulation Anna Univ Subjects. The detail syllabus for physical pharmaceutics laboratory is as follows.”
Course Objective:
- To practice the determination of fundamental properties of dosage forms of powders and dispersions.
- To study the kinetics and stability aspects of pharmaceuticals.
List of Experiments:
- Studies on polymorphs, their identification and properties.
- Determination of particle size, particle size distribution and surface area using various methods of particle size analysis.
- Determination of derived properties of powders like density, porosity, compressibility, angle of repose, etc.
- Determination of surface/interfacial tension, HLB value and critical micellar concentration (CMC) of surfactants.
- Study of rheological properties of various types of systems using different viscometers.
- Study of different types of colloids and their properties.
- Preparation of various types of suspensions and determination of their sedimentation parameters.
- Preparation and stability studies of emulsions.
- Studies on different types of complexes and determination of their stability constants.
- Studies on protein binding of drugs
- Determination of half-life, rate constant and order of reaction.
- Preparation of pharmaceutical buffers and determination of buffer capacity.
- Determination of shelf life of a product based on Arrhenius principle
- Optical Microscope
- Sieve shaker
- Anderson pipette
- Ostwalds viscometer
- Brookfield viscometer
- Stability chamber
- Bulk density apparatus
Course Outcome:
On completion of the course the students will able to
- Characterize and evaluate the properties of powders by using suitable methods.
- Plan and carryout the stability studies and determine the stability of various dosage forms.
- Calculate the rate constants and determine the various order of reactions involved in pharmaceutical systems and process.
Text Books:
- CVS Subrahmanyam, SG Vasantharaju, Laboratory Manual of Physical Pharmacy, 2nd Ed., Vallabh Prakashan, 2009.
- Manavalan, R. and Ramasamy. C. Physical Pharmaceutics 2nd Ed., Vignesh Publishers, 2015.
References:
- Eugene L. Parrott, Witold Saski, Experimental Pharmaceutics, 4th edn., Burgess Pub. Co., 1977.
- Howard C. Ansel, Pharmaceutical Calculations, 13th edn., LWW, 2009,
- Dr. U. B. Hadkar, Practical Physical Pharmacy and Physical Pharmaceutics, Nirali Prakashan, Pune,2008.
For detail syllabus of all other subjects of B.Tech Pharma, 2017 regulation do visit Pharma 3rd Sem syllabus for 2017 Regulation.
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