Molecular Pathogenesis of Infectious Diseases Biotech 6th Sem Syllabus for B.Tech 2017 Regulation Anna Univ (Professional Elective III) detail syllabus for Biotechnology (Biotech), 2017 regulation is collected from the Anna Univ official website and presented for students of Anna University. The details of the course are: course code (BT8008), Category (PE), Contact Periods/week (3), Teaching hours/week (3), Practical Hours/week (0). The total course credits are given in combined syllabus.
For all other biotech 6th sem syllabus for b.tech 2017 regulation anna univ you can visit Biotech 6th Sem syllabus for B.Tech 2017 regulation Anna Univ Subjects. For all other Professional Elective III subjects do refer to Professional Elective III. The detail syllabus for molecular pathogenesis of infectious diseases is as follows.
Course Objective:
To enable the students
- To understand about the microbial toxins and modern molecular pathogenesis
- To know about the host pathogen interaction and identifying virulence factors
- To control pathogens by modern approaches.
Unit I
For complete syllabus and results, class timetable and more pls download iStudy. Its a light weight, easy to use, no images, no pdfs platform to make students life easier.
Unit II
Host-Defense Against Pathogens and Pathogenic Strategies
Attributes and components of microbial pathogenesis, Host defense: skin, mucosa, cilia, secretions, physical movements, limitation of free iron, antimicrobial compounds, mechanism of killing by humoral and cellular defense mechanisms, complements, inflammation process, general disease symptoms, Pathogenic adaptations to overcome the above defenses.
Unit III
Molecular Pathogenesis (With Specific Examples)
Virulence, virulence factors, virulence- associated factors and virulence lifestyle factors, molecular genetics and gene regulation in virulence of pathogens, Vibrio Cholerae: Cholera toxin, coregulated pili, filamentous phage, survival E.coli pathogens: Enterotoxigenic E.coli (ETEC), labile and stable toxins, Entero- pathogenic E.coli (EPEC), type III secretion, cytoskeletal changes, intimate attachment; Enterohaemerrohogic E.coli (EHEC), mechanism of bloody diarrhoea and Hemolytic Uremic Syndrome, Enteroaggregative E.coli (EAEC). Shigella: Entry, macrophage apoptosis, induction of macropinocytosis, uptake by epithelial cells, intracellular spread, inflammatory response, tissue damage Plasmodium: Life cycle, erythrocyte stages, transport mechanism and processes to support the rapidly growing schizont, parasitiparous vacuoles, and knob protein transport, Antimalarials based on transport processes. Influenza virus: Intracellular stages, Neuraminidase and Haemagglutinin in entry, M1 and M2 proteins in assembly and disassembly, action of amantidine.
Unit IV
For complete syllabus and results, class timetable and more pls download iStudy. Its a light weight, easy to use, no images, no pdfs platform to make students life easier.
Unit V
Approaches To Control Pathogens
Classical approaches based on serotyping. Modern diagnosis based on highly conserved virulence factors, immuno and DNA-based techniques. New therapeutic strategies based on recent findings on molecular pathogenesis of a variety of pathogens, Vaccines – DNA, subunit and cocktail vaccines.
Course Outcome:
Upon completion of this course, the student will be able to understand the
- Host pathogen interactions at the level of cellular and molecular networks.
- Diagnosis of diseases through the examination of molecules.
- Modern therapeutic strategies on various pathogens.
References:
- Iglewski B.H and Clark V.L Molecular basis of Bacterial Pathogenesis, Academic Press, 1990.
- Peter Williams, Julian Ketley and George Salmond, Methods in Microbiology: Bacterial Pathogenesis, Vol. 27, Academic Press, 1998.
- Recent reviews in Infect. Immun., Mol. Microbiol., Biochem. J., EMBO etc
- Nester, Anderson, Roberts, Pearsall, Nester, Microbiology: A Human Perspective, McGraw Hill, 3rd Edition, 2001.
- Eduardo A. Groisman, Principles of Bacterial Pathogenesis, Academic Press, 2001.
For detail syllabus of all other subjects of B.Tech Biotech, 2017 regulation do visit Biotech 6th Sem syllabus for 2017 Regulation.
Dont forget to download iStudy for latest syllabus and results, class timetable and more.