Downstream Processing detail syllabus for Biotechnology (Biotech), 2017 regulation is taken from Anna University official website and presented for students of Anna University. The details of the course are: course code (BT8751), Category (PC), Contact Periods/week (3), Teaching hours/week (3), Practical Hours/week (0). The total course credits are given in combined syllabus.
For all other biotech 7th sem syllabus for b.tech 2017 regulation anna univ you can visit Biotech 7th Sem syllabus for B.Tech 2017 regulation Anna Univ Subjects. The detail syllabus for downstream processing is as follows.”
Course Objective:
To enable the students to
- Understand the methods to obtain pure proteins, enzymes and in general about product development R and D
- Have depth knowledge and hands on experience with on Downstream processes required in multi-factorial manufacturing environment in a structured and logical fashion
Unit I
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Unit II
Physical Methods of Separation
Unit operations for solid-liquid separation – filtration and centrifugation.
Unit III
Isolation of Products
Adsorption, liquid-liquid extraction, aqueous two-phase extraction, membrane separation -ultrafiltration and reverse osmosis, dialysis, precipitation of proteins by different methods.
Unit IV
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Unit V
Final Product Formulation and Finishing Operations
Crystallization, drying and lyophilization in final product formulation.
Course Outcome:
Upon success completion of this course, the students will be able to:
- Define the fundamentals of downstream processing for product recovery
- Understand the requirements for successful operations of downstream processing
- Describe the components of downstream equipment and explain the purpose of each
- Apply principles of various unit operations used in downstream processing and enhance problem solving techniques
Text Books:
- Belter, P.A., E.L. Cussler and Wei-Houhu Bioseparations – Downstream Processing for Biotechnology, John Wiley, 1988.
- Sivasankar, B. Bioseparations: Principles and Techniques. PHI, 2005.
- Asenjo, Juan A. Separation Processes in Biotechnology. CRC / Taylor and Francis, 1990.
References:
- Ghosh, Raja Principles of Bioseparations Engineering. World Scientific, 2006
- Product Recovery in Bioprocess Technology. (BIOTOL – Biotechnology by Open Learning Series). Butterworth – Heinmann / Elsevier, 2004.
For detail syllabus of all other subjects of B.Tech Biotech, 2017 regulation do visit Biotech 7th Sem syllabus for 2017 Regulation.
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