ICE

# CBM361: Physiological Modelling syllabus for ICE 2021 regulation (Professional Elective-V)

Physiological Modelling detailed syllabus for Instrumentation & Control Engineering (ICE) for 2021 regulation curriculum has been taken from the Anna Universities official website and presented for the ICE students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.

For Instrumentation & Control Engineering 6th Sem scheme and its subjects, do visit ICE 6th Sem 2021 regulation scheme. For Professional Elective-V scheme and its subjects refer to ICE Professional Elective-V syllabus scheme. The detailed syllabus of physiological modelling is as follows.

#### Unit I

INTRODUCTION TO PHYSIOLOGICAL MODELING
Approaches to modelling: The technique of mathematical modelling, classification of models, characteristics of models. Time invariant and time varying systems for physiological modelling. Introduction to physiology (homeostasis, cell biology) Modelling physical systems, linear models of physiological systems, the Laplace transform, Transfer functions and block diagram analysis Physiology.

#### Unit II

MODELING OF DYNAMIC PHYSIOLOGICAL SYSTEM
Dynamic systems and their control, modelling and block diagrams, the pupil control systems(Human Eye), general structure of control systems, the dynamic response characteristics of the pupil control system, open &close loop systems instability, automatic aperture control.

#### Unit IV

COMPARTMENTENTAL PHYSIOLOGICAL MODEL
Modeling the body as compartments, behaviour in simple compartmental system, pharmacokinetic model, and multi compartmental system. Physiological modelling: Electrical analogy of blood vessels, model of systematic blood flow and model of coronary circulation. Mathematical modelling of the system: Thermo regulation, Thermoregulation of cold bloodedness& warm bloodedness, the anatomy of thermo regulation, lumping & partial differential equations, heat transfer examples, mathematical model of the controlled process of the body.

#### Unit V

SIMULATION OF PHYSIOLOGICALSYSTEMS
Simulation of physiological systems using Open CV / MATLAB software. Biological receptors: -Introduction, receptor characteristics, transfer function models of receptors, receptor and perceived intensity. Neuromuscular model, Renal System, Drug Delivery Model.

#### Course Outcomes:

On successful completion of this course, the student will be able to

1. Explain the application of Physiological models
2. Describe the methods and techniques for analysis and synthesis of Linear and dynamic system
3. Develop differential equations to describe the compartmental physiological model
4. Describe Nonlinear models of physiological systems
5. Illustrate the Simulation of physiological systems