5th Sem, BioTech

BT3551: Bioprocess Principles syllabus for BioTech 2021 regulation

Bioprocess Principles detailed syllabus for Biotechnology (BioTech) for 2021 regulation curriculum has been taken from the Anna University official website and presented for the BioTech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.

For Biotechnology 5th Sem scheme and its subjects, do visit BioTech 5th Sem 2021 regulation scheme. The detailed syllabus of bioprocess principles is as follows.

Course Objectives:

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Unit I

OVERVIEW OF FERMENTATION PROCESSES 9
Overview of fermentation industry, general requirements of fermentation processes, basic configuration of fermentor (CSTR) and ancillaries, main parameters to be monitored and controlled in fermentation processes.

Unit II

RAW MATERIALS AND MEDIA DESIGN FOR FERMENTATION PROCESS 9
Criteria for good medium, medium requirements for fermentation processes, carbon, nitrogen, minerals, vitamins and other complex nutrients, oxygen requirements, medium formulation of optimal growth and product formation, examples of simple and complex media, design of various commercial media for industrial fermentations – medium optimization methods

Unit III

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Unit IV

METABOLIC STOICHIOMETRY AND ENERGETICS 9
Stoichiometry of cell growth and product formation, elemental balances, degrees of reduction of substrate and biomass, available electron balances, yield coefficients of biomass and product formation, maintenance coefficients energetic analysis of microbial growth and product formation, oxygen consumption and heat evolution in aerobic cultures, thermodynamic efficiency of growth.

Unit V

KINETICS OF MICROBIAL GROWTH AND PRODUCT FORMATION 9
Batch cultivation and continuous cultivation. Simple unstructured models for microbial growth, Monod model, growth of filamentous organisms, product formation kinetics – Leudeking- Piret models, substrate and product inhibition on cell growth and product formation. Biomass estimation – Direct and Indirect methods.

Course Outcomes:

Upon completion of this course the student will be able to

  • Identify suitable process instrumentation for monitoring and control of fermentor.
  • Formulate the fermentation medium to facilitate improved product production.
  • Select and apply the sterilization techniques in bioprocessing.
  • Interpret the metabolic stoichiometry in microbial processes.
  • Analyze the kinetics of microorganisms during fermentation processes.
  • Develop strategies to solve the issues in bioprocessing.

Text Books:

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Reference Books:

  1. Michael L. Shuler, Fikret Kargi, Matthew De Lisa , Bioprocess Engineering , Prentice Hall, 3rd Edition, 2017
  2. Bailey, James E. and David F. Ollis, “ Biochemical Engineering Fundamentals”, 2ndEdition. McGraw Hill , 1986.
  3. Harvey W. Blanch, Douglas S. Clark, Biochemical Engineering, CRC Press; 2nd Edition 1997

For detailed syllabus of all other subjects of Biotechnology, 2021 regulation curriculum do visit BioTech 5th Sem subject syllabuses for 2021 regulation.

For all Biotechnology results, visit Anna University BioTech all semester results direct link.

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