Molecular Biology detailed syllabus for Biotechnology (BioTech) for 2021 regulation curriculum has been taken from the Anna University official website and presented for the BioTech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Biotechnology 4th Sem scheme and its subjects, do visit BioTech 4th Sem 2021 regulation scheme. The detailed syllabus of molecular biology is as follows.
Course Objectives:
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Unit I
CHEMISTRY OF NUCLEIC ACIDS 9 Introduction to nucleic acids: Nucleic acids as genetic material, Structure and physicochemical properties of elements in DNA and RNA, Biological significance of differences in DNA and RNA. Primary structure of DNA: Chemical and structural qualities of 3,5-Phosphodiester bond. Secondary Structure of DNA: Watson & Crick model, Chargaffs rule, X-ray diffraction analysis of DNA, Forces stabilizes DNA structure, Conformational variants of double helical DNA, Hogsteen base pairing, Triple helix, Quadruple helix, Reversible denaturation and hyperchromic effect. Tertiary structure of DNA: DNA supercoiling.
Unit II
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Unit III
TRANSCRIPTION 9 Structure and function of mRNA, rRNA and tRNA. Characteristics of promoter and enhancer sequences. RNA synthesis: Initiation, elongation and termination of RNA synthesis, Proteins of RNA synthesis, Fidelity of RNA synthesis, Inhibitors of transcription, Differences in prokaryotic and eukaryotic transcription. Basic concepts in RNA world: Ribozymes, RNA processing: 5-Capping, Splicing-Alternative splicing, Poly A tail addition and base modification.
Unit IV
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Unit V
CELL DIVISION & CELL CYCLE 9 Cell division: Mitosis, Meiosis and Cytokinesis. Cell cycle: Methods in cell cycle analysis. Regulation of cell cycle – Cell cycle check points, molecules and mechanisms of cell cycle regulation. Cell cycle modulators.
Course Outcomes:
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Text Books:
- Friefelder, David. Molecular Biology. Narosa Publications, 1999
- Weaver, Robert F. Molecular Biology IInd Edition, Tata McGraw-Hill, 2003.
- Karp, Gerald Cell and Molecular Biology : Concepts and Experiments IVth Edition, John Wiley, 2005.
- Friefelder, David and George M. Malacinski Essentials of Molecular Biology IInd Edition, Panima Publishing, 1993.
Reference Books:
- Cooper GM, Hausman RE. The Cell: A Molecular approach. 7th Edition, 2015.
- Krebs JE, Goldstein ES, Kilpatrick ST. Lewins Essential GENES XII,12 th edition 2017
- Nelson DL, Cox MM. Lehninger Principles of Biochemistry. 6th Edition, 2012.
- Alberts B, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, Walter P. Molecular Biology of the cell, 6th Edition, 2014.
- Lodish H, Berk A, MatsudairaP,Kaiser CA, Krieger M, Schot MP, Zipursky L, Darnell J. Molecular Cell Biology, 6th Edition, 2007.
- Tropp, Burton E. Molecular Biology : Genes to Proteins. IIIrd Edition. Jones and Bartlett, 2008.
- Glick , B.R. and J.J. Pasternak. Molecular Biotechnology : Principles and Applications of Recombinant DNA 4th Edition. ASM, 2010.
For detailed syllabus of all other subjects of Biotechnology, 2021 regulation curriculum do visit BioTech 4th Sem subject syllabuses for 2021 regulation.
For all Biotechnology results, visit Anna University BioTech all semester results direct link.