Bioorganic Chemistry detailed syllabus for Biotechnology (BioTech) for 2021 regulation curriculum has been taken from the Anna University official website and presented for the BioTech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Biotechnology 2nd Sem scheme and its subjects, do visit BioTech 2nd Sem 2021 regulation scheme. The detailed syllabus of bioorganic chemistry is as follows.
Course Objectives:
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Unit I
BONDING AND STEREOCHEMISTRY 9 Atoms Electrons and orbitals – Covalent Bonds – Octet rule – Polar covalent Bonds -Electronegativity- formal charge – Resonance Acids and Bases – Arrhenius and Bronsted Lowry Theories – Acid Base equilibria – SP3 hybridization – Conformation analysis ethane, butane and cyclohexane – Cis- trans isomerism. Stereochemical activity around the tetrahedral carbon -optical activity – Conformation of the peptide bond.
Unit II
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Unit III
KINETICS AND MECHANISM 9 Kinetic method – Rate law and mechanism – Transition states- Intermediates – Trapping of intermediates – Microscopic reversibility – Kinetic and thermodynamic reversibility – Isotopes for detecting intermediates. Primary and secondary isotopes – the Arrhenius equation Eyring equation – AG, AS, AH, Thermodynamics of coupled reactions.
Unit IV
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Unit V
BIOORGANIC REACTIONS 9 Timing of Bond formation and fission – Acyl group transfer – C-C bond formation and fission -Catalysis of proton transfer reactions – Transfer of hydride ion – Alkyl group. Transfer – Terpene biosynthesis – Merrifield state peptide synthesis – Sanger method for peptide and DNA sequencing
Course Outcomes:
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Text Books:
- Carey, Francis A. Organic Chemistry. VIIth Edition, Tata McGraw Hill, 2009.
- Page, M.I. and Andrew Williams Organic and Bio-organic Mechanisms. Pearson, 2010.
Reference Books:
- Dugas, Hermann Bioorganic Chemistry: A Chemical Approach to Enzyme Action 3rd Edition, Springer, 2003
For detailed syllabus of all other subjects of Biotechnology, 2021 regulation curriculum do visit BioTech 2nd Sem subject syllabuses for 2021 regulation.
For all Biotechnology results, visit Anna University BioTech all semester results direct link.