Metabolomics and Metabolic Engineering detailed syllabus for Biotechnology (BioTech) for 2021 regulation curriculum has been taken from the Anna Universities official website and presented for the BioTech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Biotechnology 7th Sem scheme and its subjects, do visit BioTech 7th Sem 2021 regulation scheme. For Professional Elective-VI scheme and its subjects refer to BioTech Professional Elective-VI syllabus scheme. The detailed syllabus of metabolomics and metabolic engineering is as follows.
Course Objectives:
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Unit I
INTRODUCTION TO METABOLOMICS 9
Role of metabolomics in systems biology -application of metabolomics- Analytical methods in metabolomics – Data standards- Databases for Chemical, Spectral and Biological Data -Reconstruction of dynamic metabolic network model- examples- study of metabolome of a simple organism like E.coli.
Unit II
BIOINFORMATICS IN METABOLOMICS 9
Online databases and pipelines for metabolomics – GC-MS based metabolomics – Computational methods to compute and integrate metabolic data-software for metabolomics- metabolomics and medical sciences
Unit III
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Unit IV
METABOLIC FLUX ANALYSIS 9
Flux balance analysis, flux balance methods, group based flux balance, metabolic control analysis: overview, control coefficients, methods ofmeasuring control. Flux analysis of networks- top down approach, bottom upapproach.
Unit V
METABOLIC NETWORKS AND APPLICATIONS 9
Kinetic model of metabolic networks-Systems metabolic engineering of E.coli.Applications of Metabolomics to biology:examples and casestudies,Metabolome informatics, data integration and mining.
Course Outcomes:
Upon completion of this course,
Students will be able to
- Understand the concept of Metabolome and Metabolomics.
- Apply the Bioinformatics tools in metabolomics.
- Understand the fundamentals of Metabolic engineering.
- Analyze the metabolic pathways using flux control.
Text Books:
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Reference Books:
- Tomita M., T. Nishioka, “Metabolomics:The Frontier of Systems Biology”, Springer, 2003.
- Gregory N. Stephanopoulos, “Metabolic Engineering: Principles and Methodologies”,Academic press, First Edition, 1998.
- Wolfram Weckwerth, “Metabolomics: Methods And Protocols”, Humana Press, 2007.
- Cortassa S. “An Introduction to Metabolic and Cellular Engineering”, World scientific public company Ltd., 2002.
For detailed syllabus of all the other subjects of Biotechnology 7th Sem, visit BioTech 7th Sem subject syllabuses for 2021 regulation.
For all Biotechnology results, visit Anna University BioTech all semester results direct link.