Vaccine Technology Pharma 6th Sem Syllabus for B.Tech 2017 Regulation Anna Univ (Professional Elective IV) detail syllabus for Pharmacy (Pharma), 2017 regulation is collected from the Anna Univ official website and presented for students of Anna University. The details of the course are: course code (PY8008), Category (PE), Contact Periods/week (3), Teaching hours/week (3), Practical Hours/week (0). The total course credits are given in combined syllabus.
For all other pharma 6th sem syllabus for b.tech 2017 regulation anna univ you can visit Pharma 6th Sem syllabus for B.Tech 2017 regulation Anna Univ Subjects. For all other Professional Elective IV subjects do refer to Professional Elective IV. The detail syllabus for vaccine technology is as follows.
Course Objective:
- To provide the knowledge on conventional to recent technology of vaccine production.
- To learn the types of vaccines, its immunological effects and regulatory guidelines.
Unit I
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Unit II
Classification of Vaccines and its Preparations
Active and passive immunization; Viral/bacterial/parasite vaccine differences, methods of vaccine preparation – Live, killed, attenuated, sub unit vaccines; Vaccine technology- Role and properties of adjuvants, recombinant DNA and protein based vaccines, plant-based vaccines, edible vaccines, reverse vaccinology, combination vaccines, therapeutic vaccines; Peptide vaccines, conjugate vaccines; Cell based vaccines.
Unit III
Vaccine Research and Design
Fundamental research to rational vaccine design. Antigen identification and delivery, T-Cell expression cloning for identification of vaccine targets for intracellular pathogens, Fundamentals of Immune recognition, implications for manipulating the T-Cell repertoire, Targeting Dendritic cells; a rational approach for Vaccine development, Cellular basis of T- Cell memory, Rational design of new vectors, CpG adjuvant activity, Transcutaneous immunisation, Vaccination studies and recent advances in Malaria, Tuberculosis, HIV.
Unit IV
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Unit V
Animal Testing, Commercialisation, Quality Control
Quality control and regulations in vaccine research, In-vitro experimental validations for predictions of vaccines by software, Animal testing, Rational design to clinical trials, Large scale production, Commercialisation, ethics.
Course Outcome:
The students after completing the course
- Aware of the strategies available for developing an innovative vaccine technology with different mode of vaccine delivery.
- Able to explain the significance of critical antigens, immunogens and adjuvants in developing effective vaccines.
- Aware of the regulatory issues, guidelines for the management of production of vaccine.
Text Books:
- Ronald W. Ellis, New Vaccine Technologies, Landes Bioscience, 2001.
- Cheryl Barton, Advances in Vaccine Technology and Delivery, Espicom Business Intelligence, 2009.
- Male, David et al., Immunology, 7th Edition, Mosby Publication, 2007.
References:
- Coico, R. etal., Immunology: A Short Course, 5th Edition, Wiley – Liss, 2003.
- Parham, Peter The Immune System, 2nd Edition, Garland Science, 2005.
- Abbas, A.K. etal., The Cellular and Molecular Immunology, 6th Edition, Sanders / Elsevier, 2007.
- Weir, D.M. and Stewart, John Immunology, 8th Edition, Churchill Pvt. Ltd., 2000
For detail syllabus of all other subjects of B.Tech Pharma, 2017 regulation do visit Pharma 6th Sem syllabus for 2017 Regulation.
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