Pharmaceutical Chemistry detailed syllabus for Pharmacy (Pharma) for 2021 regulation curriculum has been taken from the Anna University official website and presented for the Pharma students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Pharmacy 3rd Sem scheme and its subjects, do visit Pharma 3rd Sem 2021 regulation scheme. The detailed syllabus of pharmaceutical chemistry is as follows.
Course Objectives:
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Unit I
STRUCTURE AND PROPERTIES 9 Atomic orbitals, molecular orbitals theory, wave equation, bonding and antibonding orbitals, hybrid orbitals, covalent bond, polarity of bonds and molecules, dipole moment, resonance, inductive, mesomeric and electromeric effects, intramolecular and intermolecular hydrogen bonding, Isomers, optical activity, stereoisomerism, specification of configuration, chirality,
Unit II
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Unit III
QUALITY CONTROL OF DRUGS AND PHARMACEUTICALS 9 Importance of quality control, significant errors, methods used for quality control, History of Pharmacopoeia, Identification and characterization of impurities in Pharmaceutical substances, Limit tests: Definition, importance, general procedure for limit test for chlorides, sulphates, iron, arsenic, heavy metals and lead with suitable examples. Identification test for Magnesium hydroxide, Ferrous sulphate, Calcium gluconate, Copper sulphate. Test for purity: Swelling power of Bentonite, Neutralizing capacity of aluminum hydroxide gel, Determination of potassium iodate and iodine in potassium Iodide Preparation of inorganic pharmaceuticals: Boric acid, Potash alum and Ferrous sulphate.
Unit IV
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Unit V
RADIOPHARMACEUTICALSAND CO-ORDINATION COMPOUNDS 9 Radio activity, Measurement of radioactivity, Properties of a, p, y radiations, Half life, radio isotopes and study of radio isotopes – Sodium iodide I131, Storage conditions, precautions & pharmaceutical application of radioactive substances. Theory of co-ordination compounds with special reference to application in Pharmacy: EDTA, Dimercaprol, Penicillamine, 1, 10- Phenanthroline.
Self Study Topics (Not for Examinations)
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Course Outcomes:
After completion of the course the student will be able to
- identifythe relationship between structure and physical propertiespharmaceutical substances and make predictions of chemical bonding along with their reaction mechanism.
- draw the structures and outline the synthesis of simple pharmaceutically active organic compounds having five and six membered heterocyclic compounds.
- describe the sources of impurities and methods to determine the impurities in inorganic drugs and pharmaceuticals.
- distinguish between various reaction mechanism and well acquainted with the synthesis of some important class of drugs.
- apply the knowledge in the handling of radiopharmaceuticals and synthesis of new drug molecule with special reference to organic, inorganic and coordination chemistry.
Text Books:
- V.Algarsamy, Pharmaceutical Organic Chemistry, Kindle edition, 2020.
- V.N.Rajasekaran, Textbook of Pharmaceutical Inorganic Chemistry Theory and Practical, CBS Publishers, 2019
- R.K. Sharma, Text Book of Coordination Chemistry, 1stEdition,Discovery Publishing House Pvt. Ltd.2011.
Reference Books:
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For detailed syllabus of all other subjects of Pharmacy, 2021 regulation curriculum do visit Pharma 3rd Sem subject syllabuses for 2021 regulation.
For all Pharmacy results, visit Anna University Pharma all semester results direct link.