Medicinal Chemistry detailed syllabus for Pharmacy (Pharma) for 2021 regulation curriculum has been taken from the Anna Universities official website and presented for the Pharma students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Pharmacy 5th Sem scheme and its subjects, do visit Pharma 5th Sem 2021 regulation scheme. For Professional Elective-I scheme and its subjects refer to Pharma Professional Elective-I syllabus scheme. The detailed syllabus of medicinal chemistry is as follows.
Course Objectives:
Download the iStudy App for all syllabus and other updates.
Unit I
PRINCIPLES OF MEDICINAL CHEMISTRY 9
Physicochemical properties in relation to biological action: Ionization, Drug distribution and pKa values and their relation to drug transport, hydrogen bonding, redox potential, surface activity and chelation. Conformational isomerism, optical and geometrical isomerism; Bioisosterism in drug design.
Unit II
DRUGS ACTING ON AUTONOMIC NERVOUS SYSTEM 9
Classification, biochemical/molecular basis of mechanism of action, structure activity relationship including stereo chemical aspects, physiochemical properties and synthesis of selected drugs belonging to the class of Cholinergics, Anticholinergics and Adrenergics.
Unit III
Download the iStudy App for all syllabus and other updates.
Unit IV
DRUGS ACTING ON CARDIOVASCULAR SYSTEM 9
Structural basis of mechanism of action, structure activity relationship including physiochemical properties and synthesis of selected drugs belonging to the class of anti-anginal, vasodilators, calcium channel blockers and cardiac glycosides.
Unit V
EICOSANOIDS, ANTIHISTAMINE AND ANTIINFLAMMATORY DRUGS 9
Synthetic procedures, uses, structure activity relationship including physicochemical properties of the following classes of drugs Antihistamines, Eicosanoids, Non-steroidal anti-inflammatory drugs (NSAIDs).
Text Books:
- Ashutosh Kar, Medicinal Chemistry, 6th Edition, New Age International (P) Ltd. Publishers, New Delhi 2015.
- Graham L. Patrick, An introduction to Medicinal Chemistry, 6th Edition, Oxford University Press, 2017.
- Ilango, K. and Valentina, P., “Text book of Medicinal Chemistry”, Vol.1 & 2, 1st & 2 nd edition, Keerthi Publishers, 2017.
Reference Books:
Download the iStudy App for all syllabus and other updates.
Course Outcomes:
The student will be able to
- Correlate the relationship between the physicochemical properties, steric properties and structural features of the drugs with its biological action.
- Explain the biochemical/molecular mechanism of action, Structure Activity Relationship, therapeutic use and depict the synthesis of drugs acting on autonomic nervous system.
- Describe the molecular basis of mechanism of action, therapeutic use, Structure Activity Relationship and synthesis of drugs acting on central nervous system.
- Illustrate the mechanism of action, therapeutic use and synthesis of drugs acting on cardiovascular system.
- Outline the chemical structure, mechanism of action, Structure Activity Relationship and therapeutic uses of eicosanoids and eicosanoid blocking agents.
- Apply the working knowledge of chemical structures, Structure Activity Relationship and molecular mechanism of drug action to suggest drug design ideas and to develop suitable techniques to synthesis different drug molecules.
For detailed syllabus of all the other subjects of Pharmacy 5th Sem, visit Pharma 5th Sem subject syllabuses for 2021 regulation.
For all Pharmacy results, visit Anna University Pharma all semester results direct link.