Biopharmaceutics and Pharmacokinetics Laboratory detailed syllabus for Pharmaceutical Technology (Pharma Tech) for 2019 regulation curriculum has been taken from the Anna Universities official website and presented for the Pharma Tech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Pharmaceutical Technology 7th Sem scheme and its subjects, do visit Pharma Tech 7th Sem 2019 regulation scheme. The detailed syllabus of biopharmaceutics and pharmacokinetics laboratory is as follows.
Course Objective:
The course aims to,
- understand the principles of pharmaceutical dosage form kinetics
- Impart the knowledge of the rate and extent of drug absorption and distribution.
List of Experiments:
- In-vitro dissolution study of the given sustained release dosage form using various dissolution media.
- Study the effect of formulation on drug release (Tablet, Solution, suspension etc.).
- Determination of effect of pH on the partition coefficient of drug(s)
- Determination of protein binding of the given drug(s) and the effect of protein binding on drug bioavailability.
- In-vitro drug absorption study using everted small intestine sac technique.
- To calculate the various Pharmacokinetic parameters from the given blood data of I.V bolus injection (one compartment model).
- To calculate various Pharmacokinetic parameters from the given urinary excretion data of I.V bolus injection using both methods (Rate of elimination and sigma minus method one compartment model).
- To determine the various Pharmacokinetic parameters from the given blood data of oral dosage form.
List of Equipment
FOR BATCH OF 30 STUDENTS
- pH Meter
- Dissolution test apparatus
- Cooling Centrifuge
- Ultra Violet Spectrophotometer
- HPLC
Course Outcome:
At the end of the course the students will be able to
- perform dissolution studies for the modified dosage forms
- estimate various pharmacokinetic parameters using plasma and urine drug level data
- predict the effects of dosage form design and routes of drug administration on drug levels in body
References:
- Vijaya Raghavan, C and Judith Justin, “Experimental Biopharmaceutics and Pharmacokinetics”, New century book house (P) Ltd., 2006.
- Burton, M.E. “Applied Pharmacokinetics and Pharmacodynamics: Principles of Therapeutics”, 4th Edition, Lippincott Williams Wilkins, 2006.
- Brahmankar, D.M. and Jaiswal, S.B. “Biopharmaceutics and Pharmacokinetics: a Treatise”, 3rd Edition, Vallabh Prakashan, 2015.
For detailed syllabus of all other subjects of Pharmaceutical Technology, 2019 regulation curriculum do visit Pharma Tech 7th Sem subject syllabuses for 2019 regulation.
For all Pharmaceutical Technology results, visit Anna University Pharma Tech all semester results direct link.