PM5511: Medicinal Chemistry Laboratory Syllabus for Pharma Tech 5th Sem 2019 Regulation Anna University

Medicinal Chemistry Laboratory detailed syllabus for Pharmaceutical Technology (Pharma Tech) for 2019 regulation curriculum has been taken from the Anna Universities official website and presented for the Pharma Tech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.

For Pharmaceutical Technology 5th Sem scheme and its subjects, do visit Pharma Tech 5th Sem 2019 regulation scheme. The detailed syllabus of medicinal chemistry laboratory is as follows.

Course Objective:

The course aims to,

• provide students with the practical laboratory skills of medicinal chemistry
• demonstrate the effect of the different synthetic methodology.
• clarify theoretical concepts of chemical synthesis of drug molecules.

List of Experiments:

1. Determination of melting point.
2. Determination of pKa.
3. Determination of partition coefficient of any medicinal compound by shake flask method.
4. Synthesis and characterization of the following drugs:
   1. Phenacetin, Antipyrine, Benzocaine
   2. Uramil, Tolbutamide
   3. Phenothiazine
   4. Isoniazid, Sulphasalazine
   5. Aspirin from salicylic acid
   6. Paracetamol from p-aminophenol
   7. Benzotriazole
   8. 2-Phenyl Indole
   9. 7-hydroxy-4 methyl coumarin
5. Any other relevant experiments based on theory.

List of Equipments

REQUIRED FOR 30 STUDENTS

• Water bath
• Hot air oven
• Vacuum filtration unit
• Reflux condenser
• Distillation unit

Course Outcome:

At the end of the course the students will be able to,

1. develop the ability to suggest suitable techniques to synthesize different drug molecules
2. learn a variety of synthetic techniques including purification methods and should gain the ability to design a synthetic scheme for a proposed drug molecule
3. demonstrate how to conduct chemical reactions within medicinal chemistry context and scientific report

References:

1. K.Yogananda Reddy, Dr.K.N. Jayaveera and Dr.S.Subramanyam, Practical Medicinal Chemistry, S.Chand Publishing, 2013.
2. Vogels Textbook of Practical Organic Chemistry, 5th edition, Pearson Publishers, 2003.
3. Mann and Saunders, Practical Organic Chemistry, 4th edition, Pearson Publishers, 2009.

For detailed syllabus of all other subjects of Pharmaceutical Technology, 2019 regulation curriculum do visit Pharma Tech 5th Sem subject syllabuses for 2019 regulation.

For all Pharmaceutical Technology results, visit Anna University Pharma Tech all semester results direct link.