Medicinal Chemistry detailed syllabus for Pharmaceutical Technology (Pharma Tech) for 2019 regulation curriculum has been taken from the Anna Universities official website and presented for the Pharma Tech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Pharmaceutical Technology 5th Sem scheme and its subjects, do visit Pharma Tech 5th Sem 2019 regulation scheme. The detailed syllabus of medicinal chemistry is as follows.
Course Objective:
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Unit I
Principles of Medicinal Chemistry
History/development of medicinal chemistry, Physicochemical properties in relation to biological action – Ionization, Drug distribution and pKa values, hydrogen bonding, protein binding, chelation, optical and geometrical isomerism, steric effect, redox potential and surface activity. Prodrugs – concepts/application of prodrug design. Introduction to QSAR.
Unit II
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Unit III
Medicinal Chemistry of Anti-Infective Agents
Structural basis of mechanism of action, structure activity relationship including stereo chemical aspects, physicochemical properties, design and synthesis of selected drugs belonging to the class of sulphonamides and sulphones, antibiotics like penicillins and cephalosporins, aminoglycosides, tetra cyclines., unclassified antibiotics – chloramphenicol and its prodrugs, peptide antibiotics, novobiocin and mupirocin, antiviral agents, anti-HIV agents, local anti-infective agents, anti-fungal agents, anti-tubercular agents, anti-protozoal agents, anthelmintics, anti-scabious and anti pedicular agents, antimalarials
Unit IV
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Unit V
Medicinal Chemistry of Anticancer Drugs
chemistry and nomenclature, structure basis of mechanism of action, structure activity relationship including stereo chemical aspects, physicochemical properties, design and synthesis of selected drugs belonging to the class of antimetabolites, DNA alkylating agents, antibiotic anticancer agents, hormonal anticancer agents, anti-tubulin inhibitors.
Course Outcome:
For the complete syllabus, results, class timetable, and many other features kindly download the iStudy App
It is a lightweight, easy to use, no images, and no pdfs platform to make students’s lives easier..
Text Books:
- Ashutosh Kar, Medicinal Chemistry, 6th Edition, New Age International (P) Ltd. Publishers, New Delhi 2015.
- Graham L. Patrick, An introduction to Medicinal Chemistry ,6th Edition, Oxford University Press, 2017.
- Ilango, K. and Valentina, P., “Text book of Medicinal Chemistry”, Vol.1, 1st edition, Keerthi Publishers,2007.
References:
- Donald J. Abraham, Burger”s Medicinal Chemistry and Drug Discovery, Vol V, 6thEdition, John Wiley and Sons, Inc., 2003.
- William O Foye, Thomas L Lemke, David A Williams Foye”s Principles of Medicinal Chemistry, 7th Edition, Wolters Kluwer Health Adis (ESP) Publisher, 2012.
- Indian Pharmacopoeia, Vol-I,7th Edition, Published by Indian Pharmacopoeia Commission India, 2014.
For detailed syllabus of all other subjects of Pharmaceutical Technology, 2019 regulation curriculum do visit Pharma Tech 5th Sem subject syllabuses for 2019 regulation.
For all Pharmaceutical Technology results, visit Anna University Pharma Tech all semester results direct link.