Protein Structure, Function and Proteomics detailed syllabus for Pharmaceutical Technology (Pharma Tech) for 2019 regulation curriculum has been taken from the Anna Universities official website and presented for the Pharma Tech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Pharmaceutical Technology 5th Sem scheme and its subjects, do visit Pharma Tech 5th Sem 2019 regulation scheme. For Professional Elective-II scheme and its subjects refer to Pharma Tech Professional Elective-II syllabus scheme. The detailed syllabus of protein structure, function and proteomics is as follows.
Course Objective:
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Unit I
Bonds, Energies, Building Blocks of Proteins
Covalent, Ionic, Hydrogen, Coordinate, hydrophobic and Vander waals interactions in protein structure. Interaction with electromagnetic radiation (radio, micro, infrared, visible, ultraviolet, X-ray) and elucidation of protein structure. Amino acids (the students should be thorough with three and single letter codes) and their molecular properties (size, solubility, charge, pKa), Chemical reactivity in relation to post-translational modification (involving amino, carboxyl, hydroxyl, thiol, imidazole groups).
Unit II
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Unit III
Tertiary Structure
Tertiary structure: Domains, folding, denaturation and renaturation, overview of methods to determine 3D structures. Quaternary structure: Modular nature, formation of complexes. Computer exercise on the above aspects
Unit IV
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Unit V
Proteomics
Introduction to the concept of proteome, components of proteomics, proteomic analysis, importance of proteomics in biological functions, protein-protein interactions and methods to study it: protein arrays, cross linking methods, affinity methods, yeast hybrid systems and protein arrays. Computer exercise on the above aspects
Course Outcome:
For the complete syllabus, results, class timetable, and many other features kindly download the iStudy App
It is a lightweight, easy to use, no images, and no pdfs platform to make students’s lives easier..
Text Books:
- Branden C. and Tooze J., “Introduction to Protein Structured” 2nd Edition, Garland Publishing, 1999.
- Creighton T.E. “Proteins” 2nd Edition. W.H. Freeman, 1993.
- Pennington, S.R and M.J. Dunn, “Proteomics: Protein Sequence to Function”. Viva Books, 2002
- Liebler, “Introduction to Proteomics” Humana Press, 2002.
References:
- Voet D. and Voet G., “Biochemistry”. 3rd Edition. John Wiley and Sons, 2008.
- Haggerty, Lauren M.”Protein Structure : Protein Science and Engineering”.Nova Science Publications, 2011.
- Williamson, Mike “How Proteins Work”. Garland Science, 2012.
For detailed syllabus of all the other subjects of Pharmaceutical Technology 5th Sem, visit Pharma Tech 5th Sem subject syllabuses for 2019 regulation.
For all Pharmaceutical Technology results, visit Anna University Pharma Tech all semester results direct link.