Medicinal Chemistry of Therapeutic Agents detailed syllabus for Pharmaceutical Technology (Pharma Tech) for 2019 regulation curriculum has been taken from the Anna Universities official website and presented for the Pharma Tech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Pharmaceutical Technology 6th Sem scheme and its subjects, do visit Pharma Tech 6th Sem 2019 regulation scheme. For Professional Elective-IV scheme and its subjects refer to Pharma Tech Professional Elective-IV syllabus scheme. The detailed syllabus of medicinal chemistry of therapeutic agents is as follows.
Course Objective:
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Unit I
Prodrugs and Metabolic Changes of Drugs
History and basic concept of prodrugs.Prodrugs of functional groups.Bioprecursor prodrugs.Chemical delivery system.General pathways of drug metabolism.Role of cytochrome P450 monooxygenase in Biotransformation, Oxidative, Reductive and Hydrolytic reaction.Conjugation reaction.Factors Affecting Drug Metabolism.
Unit II
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Unit III
Medicinal Chemistry of Antihistaminic Agents, Antiulcer Agents, Asthma and Eicosanoids
Classification, structure basis of mechanism of action, structure activity relationship including drugs acting on Histamine receptors, Antiulcer Agents.Eicosanoids biosynthesis, drug action mediated by eicosanoids, design of eicosanoid drugs.Antipyretics, anti-rheumatoid drugs and non-steroidal anti-inflammatory drugs.Asthma and Chronic Obstructive Pulmonary Disease.
Unit IV
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Unit V
Medicinal Chemistry of Vitamins, Proteins, Enzymes
Lipid-Soluble Vitamins, Water-Soluble Vitamins, Miscellaneous Considerations. Protein hydrolysate. Amino Acid Solutions, Proteins and Protein-Like Compounds, Enzymes, Blood Proteins, Impact of Biotechnology on the Development and Commercial Production of Proteins and Peptides as Pharmaceutical Products. Biotechnology-Derived Pharmaceutical Products
Course Outcome:
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Text Books:
- Ashutosh Kar “Medicinal Chemistry”, New Age International Publishers, 7th edition, 2018.
- Graham L. Patrick, “An Introduction to Medicinal Chemistry”, 5th edition, Oxford University Press, 2013.
References:
- Burger”s medicinal chemistry Vol I to IV. Wiley-Blackwell; 7th edition, 2010.
- Foye”s Principles of Medicinal Chemistry, Lippincott Williams and Wilkins; 7th Edition, 2012.
- Wilson and Giswold, “Textbook of Organic Medicinal and Pharmaceutical Chemistry”, Lippincott Williams and Wilkins; 11th edition, 2004.
- Indian/British Pharmacopoeia 2018
For detailed syllabus of all the other subjects of Pharmaceutical Technology 6th Sem, visit Pharma Tech 6th Sem subject syllabuses for 2019 regulation.
For all Pharmaceutical Technology results, visit Anna University Pharma Tech all semester results direct link.