Pharmaceutical Chemistry detail syllabus for Pharmacy (Pharma), 2017 regulation is taken from Anna University official website and presented for students of Anna University. The details of the course are: course code (PY8301), Category (PC), Contact Periods/week (3), Teaching hours/week (3), Practical Hours/week (0). The total course credits are given in combined syllabus.
For all other pharma 3rd sem syllabus for b.tech 2017 regulation anna univ you can visit Pharma 3rd Sem syllabus for B.Tech 2017 regulation Anna Univ Subjects. The detail syllabus for pharmaceutical chemistry is as follows.”
Course Objective:
- To inculcate understanding of the properties and principles of medicinal agents that originates from organic and inorganic sources and their application in pharmaceutical industry.
- To provide the basic functional group identification, molecular rearrangement, chemical bonding with their reaction mechanism.
- To provide the fundamental principles involved in the identification, preparation of pharmaceutical aids and to apply the principle of coordination compounds in pharmaceutical substances.
Unit I
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Unit II
Chemistry of Aliphatic, Aromatic and Heteroaromatic Compounds
Characteristics of organic compounds, structure, nomenclature, preparation and reaction mechanism of alkyl and aryl halides (Mechanism of SN1, SN2, E1 and E2), Huckels rule, structures, synthesis, properties and chemical reactions of benzenoid and nonbenzenoid compounds, mechanism of aromatic electrophilic and nucleophilic substitution. General principles of heterocyclic synthesis – Methods of preparation and reactions of Pyridines – Pyrroles -Thiophenes – Furans – Quinolines – Isoquinolines.
Unit III
Principles of Test for Purity in Pharmaceutical Substances
Identification and characterization of impurities in Pharmaceutical substances, Limit tests: Definition, importance, general procedure for limit test for chlorides, sulphates, iron, arsenic, heavy metals and lead with suitable examples.
Unit IV
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Unit V
Pharmaceutical Aids and Co-Ordination Compounds
Preparation and properties of various agents such as – Sodium bisulphate, Sodium metabisulphate, Sulphur dioxide, Bentonite, Magnesium stearate, Zinc stearate, Aluminium sulphate, Sodium carboxy methyl cellulose, Sodium methylparaben- Theory of co-ordination compounds with special reference to application in Pharmacy such as – EDTA, Dimercaprol, Penicillamine, 1, 10-Phenanthroline.
Course Outcome:
The student will be able to
- Identify the functional groups in pharmaceutical substances and make predictions of chemical bonding along with their reaction mechanism.
- Identify and estimate the purity of drugs and its application.
- Apply the knowledge in the development and synthesis of new drug molecule with special reference to organic, inorganic and coordination chemistry.
Text Books:
- Francis A. Carey (Author), Richard J. Sundberg, Advanced Organic Chemistry, Part A: Structure and Mechanisms 5th Edition, Springer Publishers, 2000.
- N V Chenchu Lakshmi, Pharmaceutical Inorganic chemistry: Theory and practice, 1stEdition,Pearson Education India,2012.
- R.K. Sharma, Text Book of Coordination Chemistry, 1stEdition,Discovery Publishing House Pvt. Ltd.2011.
References:
- Michael B. Smith, Jerry March, Marchs Advanced Organic Chemistry: Reactions, Mechanisms, and Structure, 6thEdition,Wiley,2007
- Lutz F. Tietze, Theophil Eicher, Ulf Diederichsen, Andreas Speicher, Reactions and Syntheses in the Organic Chemistry Laboratory, 1st Edition, Wiley – VCH,2007
- P. L. Soni, VandnaSoni, Coordination Chemistry: Metal Complexes, 1st Edition, CRC Press, 2013.
For detail syllabus of all other subjects of B.Tech Pharma, 2017 regulation do visit Pharma 3rd Sem syllabus for 2017 Regulation.
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