Medicinal Chemistry detail syllabus for Pharmacy (Pharma), 2017 regulation is taken from Anna University official website and presented for students of Anna University. The details of the course are: course code (PY8501), Category (PC), Contact Periods/week (4), Teaching hours/week (4), Practical Hours/week (0). The total course credits are given in combined syllabus.
For all other pharma 5th sem syllabus for b.tech 2017 regulation anna univ you can visit Pharma 5th Sem syllabus for B.Tech 2017 regulation Anna Univ Subjects. The detail syllabus for medicinal chemistry is as follows.”
Course Objective:
- To impart comprehensive understanding of the chemical basis of drug action including physicochemical and steric properties of drug.
- To study the classification, chemical nomenclature, generic names and synthesis of various medicinal agents.
- To understand the structure activity relationship, biochemical/molecular basis of mechanism of action and uses of drug.
Unit I
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Unit II
Drugs Acting On Synaptic and Neuro-Effector Junction Sites
Classification, biochemical/molecular basis of mechanism of action, structure activity relationship including stereo chemical aspects, physiochemical properties and synthesis of selected drugs belonging to the class of Cholinergics, Anticholinergics, Anticholinesterases and Adrenergics.
Unit III
Drugs Acting On the Central Nervous System
Classification, molecular basis of mechanism of action, structure activity relationship and synthesis of Hypnotics and Sedatives, Opioid analgesics, Anticonvulsants and Psychopharmacological agents (neuroleptics, antidepressants, anxiolytics).
Unit IV
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Unit V
Autocoids
Synthetic procedures, uses, structure activity relationship including physicochemical properties of the following classes of drugs Antihistamines, Eicosanoids, Analgesic-antipyretics, Anti -inflammatory (non-steroidal) agents.
Course Outcome:
The student will be able to
- Gain an appreciation of importance of the physical properties of drugs with respect to the ionization, solubility and efficacy of drugs, understand how changes in the chemical structure of drugs affect efficacy.
- Obtain a working knowledge of chemical structures and nomenclature, to develop the ability to suggest suitable techniques to synthesis different drug molecules.
- Understand how current drugs were developed and demonstrate the importance of chemistry in the development and application of therapeutic drugs.
Text Books:
- Ashutosh Kar, Medicinal Chemistry, 6th Edition, New Age International (P) Ltd. Publishers, New Delhi 2015.
- Graham L. Patrick, An introduction to Medicinal Chemistry ,6th Edition, Oxford University Press, 2017.
- Ilango, K. and Valentina, P., Text book of Medicinal Chemistry, Vol.1, 1st edition, Keerthi Publishers,2007.
References:
- Donald J. Abraham, Burgers Medicinal Chemistry and Drug Discovery, Vol V, 6th Edition, John Wiley and Sons, Inc., 2003.
- William O Foye, Thomas L Lemke, David A Williams Foyes Principles of Medicinal Chemistry, 7th Edition, Wolters Kluwer Health Adis (ESP) Publisher, 2012.
- Indian Pharmacopoeia, Vol-I,7th Edition, Published by Indian Pharmacopoeia Commission India, 2014.
For detail syllabus of all other subjects of B.Tech Pharma, 2017 regulation do visit Pharma 5th Sem syllabus for 2017 Regulation.
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