Downstream Processing detailed syllabus for Pharmaceutical Technology (Pharma Tech) for 2019 regulation curriculum has been taken from the Anna Universities official website and presented for the Pharma Tech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Pharmaceutical Technology 6th Sem scheme and its subjects, do visit Pharma Tech 6th Sem 2019 regulation scheme. For Professional Elective-IV scheme and its subjects refer to Pharma Tech Professional Elective-IV syllabus scheme. The detailed syllabus of downstream processing is as follows.
Course Objective:
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Unit I
Downstream Processing
Introduction to downstream processing, principles, characteristics of bio-molecules and bioprocesses. Cell disruption for product release – mechanical, enzymatic and chemical methods. Pre-treatment and stabilisation of bio-products.
Unit II
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Unit III
Isolation of Products
Adsorption, liquid-liquid extraction, aqueous two-phase extraction, membrane separation -ultrafiltration and reverse osmosis, dialysis, precipitation of proteins by different methods.
Unit IV
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Unit V
Final Product Formulation and Finishing Operations
Crystallization, Drying and Lyophilization in Final Product Formulation.
Course Outcome:
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Text Books:
- Belter, P.A., E.L. Cussler and Wei-Houhu Bioseparations – Downstream Processing for Biotechnology, John Wiley, 1988
- Ghosh, Raja Principles of Bioseparations Engineering. World Scientific, 2006.
- Roger G. Harrison, Paul W. Todd, Scott R. Rudge, and Demetri P. Petrides Bioseparations Science and Engineering Oxford University Press 2006
References:
- Michael C Flickinger Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology John Wiley and Sons 2010
- Michael R Ladisch Bioseparations Engineering John Wiley and Sons 2001
For detailed syllabus of all the other subjects of Pharmaceutical Technology 6th Sem, visit Pharma Tech 6th Sem subject syllabuses for 2019 regulation.
For all Pharmaceutical Technology results, visit Anna University Pharma Tech all semester results direct link.