IB5712: Bioinformatics Lab Syllabus for Industrial Biotech 7th Sem 2019 Regulation Anna University

Bioinformatics Lab detailed syllabus for Industrial Technology (Industrial Biotech) for 2019 regulation curriculum has been taken from the Anna Universities official website and presented for the Industrial Biotech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.

For Industrial Technology 7th Sem scheme and its subjects, do visit Industrial Biotech 7th Sem 2019 regulation scheme. The detailed syllabus of bioinformatics lab is as follows.

Course Objective:

The course aims to

• provide hands on training on data resources and bioinformatics tools
• develop skills in the analysis and interpretation of various in silico techniques such as molecular docking and homology modelling.

List of Experiments:

1. Basic Linux Commands : Directory commands, File Related commands, cut, paste, commands, sort
2. Advanced Linux commands : Redirection, Pipes, Grep filter
3. Biological Databases : Data formats and Data retrieval
4. Homology search using BLAST family of programs: BLASTp, PSIBLAST, BLASTn, Standalone BLAST
5. Multiple Sequence Alignment
6. Generating Phylogenetic trees and Bootstrapping
7. Understanding PDB structures, Ligand databases, Structure Alignment
8. Visualization tools, PyMol
9. Homology Modeling and Assessing the quality of models: SwissModel, Modeller
10. Molecular docking : Docking of macromolecules with ligands : Autodock
11. NGS data resources
12. Tools for basic analysis of NGS data

Course Outcome:

At the end of the course the students will be able to

1. have knowledge on working in Linux operating system, retrieve biological data and use bioinformatics tools
2. perform protein and nucleotide sequence analysis, next generation sequencing data analysis and phylogenetic studies
3. perform protein structural studies including modelling and docking and interpret results

References:

1. Practical Bioinformatics by Michael Agostino. Garland Science, First Edition, (2012)
2. Bioinformatics and Functional Genomics by Jonathan Pevsner. Wiley Blackwell Publications, 3rd Edition (2015)
3. RNA-seq Data Analysis: A Practical Approach, by EijaKorpelainen, JarnoTuimala, PanuSomervuo, Mikael Huss, Garry Wong. Chapman and Hall/CRC, First Edition (2014)
4. Web based tutorials for Autodock and Next Generation Sequencing Data Analysis.

For detailed syllabus of all other subjects of Industrial Technology, 2019 regulation curriculum do visit Industrial Biotech 7th Sem subject syllabuses for 2019 regulation.

For all Industrial Technology results, visit Anna University Industrial Biotech all semester results direct link.