Cancer Biology detailed syllabus for Biotechnology (BioTech) for 2021 regulation curriculum has been taken from the Anna Universities official website and presented for the BioTech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Biotechnology 5th Sem scheme and its subjects, do visit BioTech 5th Sem 2021 regulation scheme. For Professional Elective-III scheme and its subjects refer to BioTech Professional Elective-III syllabus scheme. The detailed syllabus of cancer biology is as follows.
Course Objectives:
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Unit I
FUNDAMENTALS OF CANCER BIOLOGY 9
Introduction, historical perspective, classification carcinogenesis, cancer initiation, promotion & progression, pathways of spread- Epidemology Regulation of cell cycle, mutations that cause changes in signal molecules, effects on receptor, signal switches, tumour suppressor genes, modulation of cell cycle in cancer, different forms of cancers, diet and cancer. Cancer screening and early detection, Detection using biochemical assays, tumor markers, molecular tools for early diagnosis of cancer.
Unit II
PRINCIPLES OF CARCINOGENESIS 9
Theory of carcinogenesis, Chemical carcinogenesis, metabolism of carcinogenesis, principles of Physical carcinogenesis, x-ray radiation-mechanisms of radiation carcinogenesis.
Unit III
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Unit IV
CANCER METASTASIS 9
Clinical significances of invasion, Molecular genetic of metastasis development, stromal microenvironment and carcinogenesis, dysregulation of cancer, associated genes Clinical significances of invasion, heterogeneity of metastatic phenotype, metastatic cascade, basement membrane disruption, three step theory of invasion, proteinases and tumour cell invasion.
Unit V
ADVANCES IN CANCER THERAPY 9
Different forms of therapy, chemotherapy, radiation therapy, detection of cancers, prediction of aggressiveness of cancer, advances in cancer detection. Use of signal targets towards therapy of cancer; Gene therapy. Recent technology to detect cancer diseases and advanced technology to cure cancer diseases. Targeted drug delivery methods to cure cancer.
Course Outcomes:
- Explain the development and proliferation of cancer with specific causes
- Describe the influence of carcinogenesis in the cancer development
- Identify the pathways and therapeutic targets of cancer
- Outline the steps involved in metastasis and tumour cell invasion
- Develop novel drugs and technologies for the treatment of cancer
- Summarize the microenvironment of cancer cells and their attack on immune cells
Text Books:
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Reference Books:
- King, Roger J.B. “Cancer Biology” Addison Wesley Longman, 1996.
- Ruddon, Raymond W. “ Cancer Biology” IIIrd Edition . Oxford University Press, 1995
- Margaret A. Knowles, Peter J Selby, An Introduction to Cellular and Molecular Biology of Cancer, 4th Edition, Oxford Medical Publication, 1991.
- https://oncouasd.files.wordpress.com/2014/09/cancer-principles-and-practice-of-oncology-6e.pdf
- https://archive.org/details/biologyofcancera00burc.
- http://csbl.bmb.uga.edu/mirrors/JLU/DragonStar2017/download/introduction-to-cancer-biology.pdf
For detailed syllabus of all the other subjects of Biotechnology 5th Sem, visit BioTech 5th Sem subject syllabuses for 2021 regulation.
For all Biotechnology results, visit Anna University BioTech all semester results direct link.