Principles of Tissue Engineering detailed syllabus for Biomedical Engineering (BME) for 2021 regulation curriculum has been taken from the Anna Universities official website and presented for the BME students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Biomedical Engineering 5th Sem scheme and its subjects, do visit BME 5th Sem 2021 regulation scheme. For Professional Elective-I scheme and its subjects refer to BME Professional Elective-I syllabus scheme. The detailed syllabus of principles of tissue engineering is as follows.
Course Objectives:
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Unit I
INTRODUCTION TO CELL BIOLOGY
Cell types – Progenitor cells – Cell growth and differentiation – Cell culture: Expansion – Transfer -Storage and Characterization – Cell signalling molecules – Growth factors – Cell attachment: Differential cell adhesion, Receptor-ligand binding – Cell surface markers.
Unit II
FUNDAMENTALS OF TISSUE ENGINEERING
History and scope of tissue engineering – Tissue organization – Tissue types: Epithelial, Connective – Vascularity and angiogenesis – Wound healing – Extra Cellular Matrix: Matrix molecules and their ligands – Tissue culture – Materials in tissue engineering.
Unit III
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Unit IV
ENGINEERING METHODS AND DESIGN
Soft lithography – Self-assembled monolayer, Micro contact printing, Micro fluidic patterning -Laminar flow patterning – Cell interaction with Polymer scaffolds and gels – Polymer scaffolds fabrications: Electro spinning – Solvent casting and particulate leaching – Micro fabrication of cell seeded scaffolds.
Unit V
APPLICATION OF TISSUE ENGINEERING
Replacement Engineering: Bone, cartilage, skin, blood, pancreas, kidney, heart valve and liver -Regenerative engineering: Peripheral Nerve regeneration, Cardiac tissue regeneration, Muscle regeneration – Regulation, Commercialization and Patenting.
Course Outcomes:
At the end of the course, the student should be able to:
- Understand the basic concepts of tissue engineering
- Acquire ability to function on multi-disciplinary teams
- Apply the knowledge of professional and ethical responsibility in use of stem cells and gene therapy in creating tissue engineered therapies
- Design and develop different biomaterial in tissue engineering application
- Gain knowledge in research or clinical application on tissue repair/ engineering
Text Books:
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Reference Books:
- Gary E. Wnek, Gary L Browlin, “Encyclopedia of Biomaterials and Biomedical Engineering”, Marcel Dekker Inc, New York, 2008.
- R. Lanza, Anthony Atala (Eds), “Essential of Stem Cell Biology”, Academic Press, USA, 2013.
- R. Lanza, Anthony Atala,“Handbook of Stem Cells’’, Academic Press, USA, 2012.
For detailed syllabus of all the other subjects of Biomedical Engineering 5th Sem, visit BME 5th Sem subject syllabuses for 2021 regulation.
For all Biomedical Engineering results, visit Anna University BME all semester results direct link.