7th Sem, BioTech

BT3751: Downstream Processing syllabus for BioTech 2021 regulation

Downstream Processing detailed syllabus for Biotechnology (BioTech) for 2021 regulation curriculum has been taken from the Anna University official website and presented for the BioTech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.

For Biotechnology 7th Sem scheme and its subjects, do visit BioTech 7th Sem 2021 regulation scheme. The detailed syllabus of downstream processing is as follows.

Course Objectives:

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Unit I

INTRODUCTION 9
Introduction to downstream processing, principles, characteristics of bio-molecules and bioprocesses. Cell disruption for product release – mechanical, enzymatic and chemical methods. Pre treatment and stabilisation of bio-products.

Unit II

PHYSICAL METHODS OF SEPARATION 9
Unit operations for solid-liquid separation – filtration and centrifugation.

Unit III

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Unit IV

PRODUCT PURIFICATION 9
Chromatography – principles, instruments and practice, adsorption, reverse phase, ion exchange, size exclusion, hydrophobic interaction, bio-affinity and pseudo affinity chromatographic techniques.

Unit V

FINAL PRODUCT FORMULATION AND FINISHING OPERATIONS 9
Crystallization, drying and lyophilization in final product formulation

Course Outcomes:

Upon success completion of this course, the students will be able to:

  • Define the fundamentals of downstream processing for product recovery
  • Understand the requirements for successful operations of downstream processing
  • Describe the components of downstream equipment and explain the purpose of each
  • Apply principles of various unit operations used in downstream processing and enhance problem solving techniques

Text Books:

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Reference Books:

  1. Raja Ghosh “Principles of Bioseparations Engineering”. World Scientific, 2006
  2. Michael R.Ladisch Bioseparations Engineering: Principles, practice and Economics, Wiley-Interscience,1st Edition,2001.
  3. Product Recovery in Bioprocess Technology”. (BIOTOL – Biotechnology by Open Learning Series). Butterworth – Heinmann / Elsevier, 2004.

For detailed syllabus of all other subjects of Biotechnology, 2021 regulation curriculum do visit BioTech 7th Sem subject syllabuses for 2021 regulation.

For all Biotechnology results, visit Anna University BioTech all semester results direct link.

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