Downstream Processing detailed syllabus for Biotechnology & Biochemical Engineering (BBE) for 2021 regulation curriculum has been taken from the Anna University official website and presented for the BBE students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Biotechnology & Biochemical Engineering 7th Sem scheme and its subjects, do visit BBE 7th Sem 2021 regulation scheme. The detailed syllabus of downstream processing is as follows.
Course Objectives:
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Unit I
INTRODUCTION
Introduction to downstream processing, principles, characteristics of bio-molecules and 9 bioprocesses. Cell disruption for product release – mechanical, enzymatic and chemical methods. Pre treatment and stabilisation of bio-products.
Unit II
PHYSICAL METHODS OF SEPARATION
Unit operations for solid-liquid separation – filtration and centrifugation.
Unit III
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Unit IV
PRODUCT PURIFICATION 9
Chromatography – principles, instruments and practice, adsorption, reverse phase, ion exchange, size exclusion, hydrophobic interaction, bio-affinity and pseudo affinity chromatographic techniques.
Unit V
FINAL PRODUCT FORMULATION AND FINISHING OPERATIONS 9
Crystallization, drying and lyophilization in final product formulation
Course Outcomes:
Upon success completion of this course, the students will be able to:
- Define the fundamentals of downstream processing for product recovery
- Understand the requirements for successful operations of downstream processing
- Describe the components of downstream equipment and explain the purpose of each
- Apply principles of various unit operations used in downstream processing and enhance problem solving techniques
Text Books:
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Reference Books:
- Raja Ghosh “Principles of Bioseparations Engineering”. World Scientific, 2006
- Michael R.Ladisch Bioseparations Engineering: Principles, practice and Economics, Wiley-Interscience,1st Edition,2001.
- Product Recovery in Bioprocess Technology”. (BIOTOL – Biotechnology by Open Learning Series). Butterworth – Heinmann / Elsevier, 2004.
For detailed syllabus of all other subjects of Biotechnology & Biochemical Engineering, 2021 regulation curriculum do visit BBE 7th Sem subject syllabuses for 2021 regulation.
For all Biotechnology & Biochemical Engineering results, visit Anna University BBE all semester results direct link.