Human Genetics detailed syllabus for Biotechnology (BioTech) for 2021 regulation curriculum has been taken from the Anna Universities official website and presented for the BioTech students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Biotechnology 5th Sem scheme and its subjects, do visit BioTech 5th Sem 2021 regulation scheme. For Professional Elective-III scheme and its subjects refer to BioTech Professional Elective-III syllabus scheme. The detailed syllabus of human genetics is as follows.
Course Objectives:
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Unit I
INTRODUCTION
N | 9
History of genetics – Mendel’s principles and experiments, segregation, multiple alleles -Independent Assortments, Genotypic interactions, epistasis and Sex chromosomes, Sex determination, Dosage compensation, sex linkage and pedigree analysis
Unit II
COMPLEX TRAITS 9
Approaches to analysis of complex traits- ‘Nature vs nurture’, role of family and shared environment, monozygotic and dizygotic twins and adoption studies – Polygenic inheritance of continuous (quantitative) traits and discontinuous {dichotomous) traits – Genetic susceptibility in complex traits – Estimation of genetic components of multifactorial traits: emperic risk, heritability, coefficient of relationship, application of Baye’s theorem.
Unit III
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Unit IV
APPLIED GENETICS 9
Genetic linkage and gene mapping – Genetic polymorphism, RFLP, SNP, STRP – Physical mapping of the human genome – Transcriptional mapping – Molecular techniques in human chromosome analysis (FISH, GISH, CGH, SKY).
Unit V
CLINICAL GENETICS 9
Genetic basis of syndromes and disorders – Monogenic diseases: Cystic fibrosis, Marfan syndrome – Inborn errors of metabolism: Phenylketonuria, Mucopolysaccharidosis, Galactosemia – Syndromes due to triplet nucleotide expansion: Muscle genetic disorders, Sickle cell anemia, Thalassemias, Colour Blindness, Retinitis pigmentosa.
Course Outcomes:
Upon completion of the course, students will be able to
- Understand the concept of Mendelian and non-Mendelian genetics.
- Know the concepts of complex traits inheritance and mechanism of sex determination.
- Discuss clearly about the chromosomal pathologies.
- Describe the principles behind DNA fingerprinting methodologies using molecular markers RFLP, RAPD, STRP, and SNP’s.
- Applying the genetic technologies knowledge in industries related to pharmaceuticals, biotechnology, and diagnostic clinics.
- To bring awareness to human society on various genetic disorders, its inheritance patterns and to develop the methods, and techniques of fighting against the diseases.
Text Books:
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Reference Books:
- Benjamin A. Pierce, “Genetics: A Conceptual Approach”, 7th Edition, Macmillan Learning, 2020.
- William S Klug, Michael Cummings, Charlotte A. Spencer, Michael A Palladino & Darrell Killian, “Concepts of Genetics”, 12th Edition Pearson, 2019.
- D. Peter Snustad, Michael J. Simmons, “Principles of Genetics”, 7th Edition, published by Wiley, 2015.
For detailed syllabus of all the other subjects of Biotechnology 5th Sem, visit BioTech 5th Sem subject syllabuses for 2021 regulation.
For all Biotechnology results, visit Anna University BioTech all semester results direct link.