Biopharmaceutics and Pharmacokinetics Laboratory detail syllabus for Pharmacy (Pharma), 2017 regulation is taken from Anna University official website and presented for students of Anna University. The details of the course are: course code (PY8711), Category (PC), Contact Periods/week (4), Teaching hours/week (0), Practical Hours/week (0). The total course credits are 4.
For all other pharma 7th sem syllabus for b.tech 2017 regulation anna univ you can visit Pharma 7th Sem syllabus for B.Tech 2017 regulation Anna Univ Subjects. The detail syllabus for biopharmaceutics and pharmacokinetics laboratory is as follows.”
Course Objective:
- To impart the knowledge of the rate and extent of drug absorption and distribution.
List of Experiments:
- In-vitro dissolution study of the given sustained release dosage form using various dissolution media.
- Study the effect of formulation on drug release (Tablet, Solution, suspension etc.).
- Determination of effect of pH on the partition co-efficient of drug(s)
- Determination of protein binding of the given drug(s) and the effect of protein binding on drug bioavailability.
- In-vitro drug absorption study using everted small intestine sac technique.
- To calculate the various Pharmacokinetic parameters from the given blood data of I.Vbolus injection (one compartment model).
- To calculate various Pharmacokinetic parameters from the given urinary excretion data of I.V bolus injection using both methods (Rate of elimination and sigma minus method one compartment model).
- To determine the various Pharmacokinetic parameters from the given blood data of oral dosage form.
List of Equipment for Batch of 30 Students
- pH Meter
- Dissolution test apparatus
- Cooling Centrifuge
- Ultra Violet Spectrophotometer
- HPLC
Course Outcome:
On completion of the course the students able to
- Perform dissolution studies for the modified dosage forms.
- Estimate various pharmacokinetic parameters using plasma and urine drug level data.
- Predict the effects of dosage form design and routes of drug administration on drug levels in body.
References:
- Vijaya Raghavan, C and Judith Justin. Experimental Biopharmaceutics and Pharmacokinetics, New century book house (P) Ltd., 2006
- Burton, M.E. Applied Pharmacokinetics and Pharmocodynamics: Principles of Therapeutics 4th Edition, Lippincott Williams Wilkins, 2006.
- Brahmankar, D.M. and Jaiswal, S.B. Biopharmaceutics and Pharmacokinetics: a Treatise 3rd Edition, Vallabh Prakashan, 2015.
For detail syllabus of all other subjects of B.Tech Pharma, 2017 regulation do visit Pharma 7th Sem syllabus for 2017 Regulation.
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