Biofluids and Dynamics Bme 6th Sem Syllabus for BE 2017 Regulation Anna Univ (Professional Elective II) detail syllabus for Biomedical Engineering (Bme), 2017 regulation is collected from the Anna Univ official website and presented for students of Anna University. The details of the course are: course code (BM8003), Category (PE), Contact Periods/week (3), Teaching hours/week (3), Practical Hours/week (0). The total course credits are given in combined syllabus.
For all other bme 6th sem syllabus for be 2017 regulation anna univ you can visit Bme 6th Sem syllabus for BE 2017 regulation Anna Univ Subjects. For all other Professional Elective II subjects do refer to Professional Elective II. The detail syllabus for biofluids and dynamics is as follows.
Course Objective:
The student should be made
- To understand the basics of fluid mechanics,
- To analyze cellular, ocular, cardiovascular and respiratory fluid mechanics
- To learn mathematical modelling of fluid biological systems.
Unit I
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Unit II
Cellular and Occular Mechanics
Cellular Biomechanics – Eukaryotic cell architecture, Cytoskeleton, Cell-matrix interactions, Mechanical property measurement – Atomic Force microscopy, Optical Trapping, Magnetic bead microrheometry, Micropipette aspiration, Models of cellular biomechanical behavior, Computational model of a chondrocyte in its matrix, Mechanotransduction, Techniques for mechanical stimulation of the cells, Tissue cell mechanobiology – Endothelial, smooth muscle cells, Chondrocytes, Osteoblasts, Ocular Biomechanics – Occular anatomy, Biomechanics of Glaucoma, Ocular blood flow.
Unit III
Blood Rheology and Blood Vessel Mechanics
Viscometry, Elements of Blood, Blood characteristics – Viscosity of blood, Einsteins equation, Biomechanics of red cell membrane, Apparent and relative viscosity, Blood viscosity variation,Casson”s equation, Rheology of Blood In Micro vessels – Fahraeus-Lindquist effect and its inversion, Anatomy and physiology of blood vessels, Arterial wall as membrane – Uniaxial loading, Biaxial loading, Torsion, Hemodynamics of Large arteries – Ventricular outflow and the aorta, Pressure-flow relations and Vascular Impedance, Wave propagation and reflection.
Unit IV
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Unit V
Computational Fluid Dynamics
Computational fluid dynamics – CFD Code, Problem solving with CFD, Conservation Laws of Fluid Motion and Boundary Conditions, Turbulence and its modelling, The Finite Volume Method for Diffusion Problems and Convection-Diffusion Problems, Solution Algorithms for Pressure-Velocity Coupling in steady flows, Solution of Discretized Equations, The Finite Volume Method for Unsteady flows, Implementation of Boundary Conditions Application – Multiphysics computational models for cardiac flow and virtual cardiography.
Course Outcome:
At the end of the course, the student should be able to:
- Understand the basics of Fluid Mechanics
- Construe the intracellular fluid mechanics and ocular mechanics.
- Describe the rheology of blood and mechanics of blood vessels.
- Elucidate on cardiorespiratory mechanics and space medicine.
- Develop mathematical models of biological systems with fluids
Text Books:
- Krishnan B. Chandran, Ajit P. Yoganathan, Stanley E. Rittgers, Biofluid Mechanics- The human circulation, CRC Taylor and Francis, 2007.
- Y.C Fung, Biomechanics- Mechanical properties of living tissues, 2nd Edition, SpringerVerlag, 1993.
- Jeffery R. Davis et. Al., Fundamentals of Aerospace Medicine, Wolter Kluwer Health, Lippincott Williams and Wilkins, 2008
References:
- Jung HeeSeo, Vijay Vedula, Theodore Abraham and Rajat Mittal, Multiphysics computational models for cardiac flow and virtual cardiography, Int. J. Numer. Meth. Biomed. Engng. (2013) Published online in Wiley Online Library
- Lee Waite, Jerry Fine, Applied Biofluid Mechanics, McGraw Hill, 2007
- John K-J Li, Dynamics of Vascular System, World Scientific, 2004
- C. Ross Ethier, Craig A Simmons, Introduction to Biomechanics- From Cells to Organisms, Cambridge Texts in Biomedical Engineering, 2007
- H K Versteeg, W Malalasekera, An Introduction to Computational Fluid Dynamics The Finite Volume Method, Longman Scientific and Technical, 1995
For detail syllabus of all other subjects of BE Bme, 2017 regulation do visit Bme 6th Sem syllabus for 2017 Regulation.
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