Bioconjugate Technology and Applications Biotech 7th Sem Syllabus for B.Tech 2017 Regulation Anna Univ (Professional Elective V) detail syllabus for Biotechnology (Biotech), 2017 regulation is collected from the Anna Univ official website and presented for students of Anna University. The details of the course are: course code (BT8020), Category (PE), Contact Periods/week (3), Teaching hours/week (3), Practical Hours/week (0). The total course credits are given in combined syllabus.
For all other biotech 7th sem syllabus for b.tech 2017 regulation anna univ you can visit Biotech 7th Sem syllabus for B.Tech 2017 regulation Anna Univ Subjects. For all other Professional Elective V subjects do refer to Professional Elective V. The detail syllabus for bioconjugate technology and applications is as follows.
Course Objective:
To enable the students
- To understand the functional targets and chemistry of active groups.
- To gain knowledge about the linkers and cleavable reagent systems.
- To know about enzyme, nucleic acid modification and its application in bioconjugation
Unit I
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Unit II
Chemistry of Active Groups
Amine reactive chemical reactions – Thiol reactive chemical reactions – carboxylate reactive chemical reactions – hydroxyl reactive chemical reactions – aldehyde and ketone reactive chemical reactions – Photoreactive chemical reactions.
Unit III
Bioconjugate Reagents
Zero length cross linkers – Homobifunctional cross linkers – Heterobifunctional cross linkers -Trifunctional cross linkers – Cleavable reagent systems – tags and probes.
Unit IV
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Unit V
Bioconjugate Applications
Preparation of Hapten-carrier Immunogen conjugates – antibody modification and conjugation immunotoxin conjugation techniques – liposome conjugated and derivatives- Colloidal – gold-labeled proteins – modification with synthetic polymers.
Course Outcome:
Upon completion of this course, the student would know about
- Joining of two molecules to form a hybrid conjugate with the help of linkers.
- Active groups of various chemical reactions and targets of the functional groups.
- Antibody modification and conjugation.
References:
- Bioconjugate Techniques, G.T. Hermanson, Academic Press, 1999.
For detail syllabus of all other subjects of B.Tech Biotech, 2017 regulation do visit Biotech 7th Sem syllabus for 2017 Regulation.
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