Bioreactor Engineering detailed syllabus for Biotechnology & Biochemical Engineering (BBE) for 2021 regulation curriculum has been taken from the Anna Universities official website and presented for the BBE students. For course code, course name, number of credits for a course and other scheme related information, do visit full semester subjects post given below.
For Biotechnology & Biochemical Engineering 5th Sem scheme and its subjects, do visit BBE 5th Sem 2021 regulation scheme. For Professional Elective-I scheme and its subjects refer to BBE Professional Elective-I syllabus scheme. The detailed syllabus of bioreactor engineering is as follows.
Course Objectives:
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Unit I
DESIGN AND ANALYSIS OF BIOREACTORS 9
Design and operation of novel bioreactors-Air-lift loop reactors, Fluidized bed-bioreactors, packed bed reactor, Bubble column reactor, stability analysis of bioreactors
Unit II
BIOREACTOR SCALE-UP 9
Oxygen mass transfer in bioreactors – microbial oxygen demands; methods for the determination of mass transfer coefficients; mass transfer correlations. Scale up criteria for bioreactors based on oxygen transfer, power consumption and impeller tip speed, other scale up criteria
Unit III
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Unit IV
MODERN BIOTECHNOLOGICAL PROCESSES 9
Recombinant cell culture processes, guidelines for choosing host-vector systems, plasmid stability in recombinant cell culture, limits to over expression, Modelling of recombinant bacterial cultures; bioreactor strategies for maximizing product formation; Bioprocess design considerations for plant and animal cell cultures
Unit V
MODELLING AND SIMULATION OF BIOPROCESSES 9
Study of structured models for analysis of various bioprocess – compartmental models, models of cellular energetics and metabolism, single cell models, plasmid replication and plasmid stability model. Dynamic simulation of batch, fed batch, steady and transient culture metabolism.
Course Outcomes:
The students will be able to
- Develop knowledge on various bioreactors.
- Classify modern biotechnological process in host vector systems.
- Understand methods to calculate oxygen and mass transfer coefficients in bioreactors.
- Assess on-line data analysis for measurement of important physico-chemical and biochemical parameters in bioreactors.
- Analyze structured models for analysis of various bioprocesses.
- Design of various instrumentation for monitoring and control of bioreactors
Text Books:
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Reference Books:
- P.Stanbury, A.Whitaker,SJ Hall “Principles of fermentation technology”, Second edition, ElsvierPergamon Press,2010.
- Pauline Doran,”Bioprocess Engineering Principles”, Academic Press, 2010.
- ElmarHeinzle, Arno P.Biwer, “Development of Sustainable Bioprocess: Modelling and Assessment”, Wiley, 2007.
- Bjorn K.Lyderson, Nancy Ade’lia and Kim Nelson,”Bioprocess engineering (handcover)”,Wiley Interscience, 2014
For detailed syllabus of all the other subjects of Biotechnology & Biochemical Engineering 5th Sem, visit BBE 5th Sem subject syllabuses for 2021 regulation.
For all Biotechnology & Biochemical Engineering results, visit Anna University BBE all semester results direct link.