Bioorganic Chemistry Syllabus for B.Tech Third sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course. The detailed syllabus for Bioorganic Chemistry B.Tech 2016-2017 (R13) thirdsem is as follows
OBJECTIVES: To enable the students
- To know in detail about the elements of atom, charges and their bonding rule.
- To understand the various kinetic properties and types of reaction mechanisms
- To understand the possible bio-organic reactions involved in biosynthesis
UNIT I : BONDING AND STEREOCHEMISTRY [9 Hours]
Atoms Electrons and orbitals – Covalent Bonds – Octet rule – Polar covalant Bonds – Electronegativity- formal charge – Resonance Acids and Bases – Arrhenius and Bronsted Lowry Theories – Acid Base equilbria – SP3 hybridization – Conformations analysis ethane, butane and cyclohexane – Cis- trans isomerism. Stereochem activity around the tetrahedral carbon – optical activity – Conformation of the peptide bond.
UNIT II : MECHANISMS OF SUBSTITUTION AND ADDITION REACTIONS [9 Hours]
SN1 and SN2 reactions on tetrahedral carbon- nucleophiles- mechanism steric effects – nucleophilic addition on Acetals and ketals -Aldehyde and ketone groups – reactions of carbonyl group with amines- acid catalyzed ester hydrolysis – Saponification of an esterhydrolysis of amides. Ester enolates – claisen .condensation – Michael condensation.
UNIT III : KINETICS AND MECHANISM [9 Hours]
Kinetic method – Rate law and mechanism – Transition states- Intermediates – Trapping of intermediates – Microscopic reversibility – Kinetic and thermodynamic reversibility – Isotopes for detecting intermediates. Primary and secondary isotopes – the Arrhenius equation Eyring equation – ΔG, ΔS, ΔH, Thermodynamics of coupled reactions.
[TOTAL : 45 PERIODS]
OUTCOME:
On completion of this course, the students will learn the basics principles of chemical Bonding, Stereochemistry of Bio-organic molecules and their kinetics, mechanisms of reactions and catalysis.
TEXT BOOKS:
- Carey, Francis A.” Organic Chemistry”. 7th Edition, Tata MCGraw Hill, 2009.
- Page, M.I. and Andrew Williams “Organic and Bio-organic Mechanisms”. Pearson, 2010.
REFERENCE:
- Dugas, Hermann “ Bioorganic Chemistry : A Chemical Approach to Enzyme Action” 3rd Edition, Springer, 2003.
For all other B.Tech BT 3rd sem syllabus go to Anna University B.Tech BIOTECHNOLOGY 3rd Sem Course Structure for (R13) Batch. All details and yearly new syllabus will be updated here time to time. Subscribe, like us on facebook and follow us on google plus for all updates.
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