Bioinformatics and Computational Biology Based for Biotechnologists Syllabus for B.Tech Seventh sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.
The detailed syllabus for Bioinformatics and Computational Biology Based B.Tech 2016-2017 (R13) seventhsem is as follows
OBJECTIVES:
- To improve the programming skills of the student
- To let the students know the recent evolution in biological science.
UNIT : I [9 Hours]
Introduction to Operating systems, Linux commands, File transfer protocols ftp and telnet, Introduction to Bioinformatics and Computational Biology, Biological sequences, Biological databases, Genome specific databases, Data file formats, Data life cycle, Database management system models, Basics of Structured Query Language (SQL).
UNIT : II [9 Hours]
Sequence Analysis, Pairwise alignment, Dynamic programming algorithms for computing edit distance, string similarity, shotgun DNA sequencing, end space free alignment. Multiple sequence alignment, Algorithms for Multiple sequence alignment, Generating motifs and profiles, Local and Global alignment, Needleman and Wunsch algorithm, Smith Waterman algorithm, BLAST, PSIBLAST and PHIBLAST algorithms.
UNIT : III [8 Hours]
Introduction to phylogenetics, Distance based trees UPGMA trees, Molecular clock theory, Ultrametric trees, Parsimonious trees, Neighbour joining trees, trees based on morphological traits, Bootstrapping. Protein Secondary structure and tertiary structure prediction methods, Homology modeling, abinitio approaches, Threading, Critical Assessment of Structure Prediction, Structural genomics.
TOTAL : 45 PERIODS
OUTCOMES: Upon completion of this course, students will be able to
- Develop bioinformatics tools with programming skills.
- Apply computational based solutions for biological perspectives.
- Pursue higher education in this field.
- Practice life-long learning of applied biological science.
TEXT BOOKS:
- Lesk, A. K., “Introduction to Bioinformatics” 4th Edition, Oxford University Press, 2013
- Dan Gusfield, “Algorithms on Strings, Trees and Sequences: Computer Science and Computational Biology” Cambridge University Press, 1997.
- Durbin, R., Eddy, S., Krogh, A., and Mitchison, G., “Biological Sequence Analysis
Probabilistic Models of proteins and nucleic acids” Cambridge, UK: Cambridge University Press, 1998. - Mount, D.W., “Bioinformatics Sequence and Genome Analysis” 2nd Edition, Cold Spring Harbor Laboratory Press, 2004
- Tindall, J., “Beginning Perl for Bioinformatics: An introduction to Perl for Biologists” 1st Edition, O’Reilly Media, 2001
REFERENCE:
- Baldi, P. and Brunak, S., “Bioinformatics: The Machine Learning Approach” 2nd Edition, MIT Press, 2001.
For all other B.Tech BT 7th sem syllabus go to Anna University B.Tech BIOTECHNOLOGY 7th Sem Course Structure for (R13) Batch. All details and yearly new syllabus will be updated here time to time. Subscribe, like us on facebook and follow us on google plus for all updates.
Do share with friends and in case of questions please feel free drop a comment.