Bioconjugate Technology and Applications Based for Biotechnologists Syllabus for B.Tech Seventh sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.
The detailed syllabus for Bioconjugate Technology and Applications B.Tech 2016-2017 (R13) seventhsem is as follows
OBJECTIVES: To enable the students
- To understand the functional targets and chemistry of active groups.
- To gain knowledge about the linkers and cleavable reagent systems.
- To know about enzyme, nucleic acid modification and its application in bioconjugation
UNIT I : FUNCTIONAL TARGETS [9 Hours]
Modification of Amino Acids, Peptides and Proteins – Modification of sugars, polysaccharides and glycoconjugates – modification of nucleic acids and oligonucleotides.
UNIT II : CHEMISTRY OF ACTIVE GROUPS [9 Hours]
Amine reactive chemical reactions – Thiol reactive chemical reactions – carboxylate reactive chemical reactions – hydroxyl reactive chemical reactions – aldehyde and ketone reactive chemical reactions – Photoreactive chemical reactions.
UNIT III : BIOCONJUGATE REAGENTS [9 Hours]
Zero length cross linkers – Homobifunctional cross linkers – Heterobifunctional cross linkers – Trifunctional cross linkers – Cleavable reagent systems – tags and probes.
TOTAL : 45 PERIODS
OUTCOMES: Upon completion of this course, the student would know about
- Joining of two molecules to form a hybrid conjugate with the help of linkers.
- Active groups of various chemical reactions and targets of the functional groups.
- Antibody modification and conjugation.
TEXTBOOK:
- Bioconjugate Techniques, G.T. Hermanson, Academic Press, 1999.
For all other B.Tech BT 7th sem syllabus go to Anna University B.Tech BIOTECHNOLOGY 7th Sem Course Structure for (R13) Batch. All details and yearly new syllabus will be updated here time to time. Subscribe, like us on facebook and follow us on google plus for all updates.
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