Cancer Biology and Therapeutics for Biotechnologists Syllabus for B.Tech Sixth sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.
The detailed syllabus for Cancer Biology and Therapeutics B.Tech 2016-2017 (R13) sixthsem is as follows
OBJECTIVES: To enable the students to understand
- Basic biology of cancer
- Impact of antibodies against cancer in the human body leading to more effective
treatments - Enhanced immunology based detection methods and imaging techniques
- Development of cell based and cytokine based immunotherapy against cancer.
UNIT I : OVERVIEW AND ELEMENTS OF THE CANCER IMMUNOLOGY [5 Hours]
Role of Immune system in cancer – role of individual immune cell types against cancer – role of cytokines in immune cell programming against cancer.
UNIT II : CANCER ANTIGENS [10 Hours]
Source of cancer antigens – clonal (viral)/mutational origin – detection and processing by immune cell types through MHC – T-cell receptor – B-cell receptor and cytokines involved – cancer cell death strategies induced by immune cells.
UNIT III : ANTIBODY DEVELOPMENT AGAINST CANCER ANTIGENS [12 Hours]
Role of VDJ recombination – Causes for the failure to recognize cancer antigen – roles and mechanism of immune self-tolerance machinery and Immune surveillance – Correlating pathway specific deregulations in self-tolerance machinery and Immune surveillance as a risk factor/potential target towards autoimmune disorders and cancer.
TOTAL : 45 PERIODS
OUTCOMES: The course would facilitate the students
- To appreciate the role of immune system in cancer
- To describe self – tolerance machinery and immune surveillance
- To understand the cancer microenvironment and its influence on immune cells
- To have awareness on medical applications of cytokines and immune cells against cancer
TEXT BOOKS:
- Thomas J. Kindt, Barbara A. Osborne and Richard Goldsby. Kuby Immunology, 6th edition. W.H. Freeman, 2007
- Stella Pelengaris and Michael Khan. The Molecular Biology of Cancer, 2nd edition. Wiley – Blackwell, 2013
REFERENCES:
- Roitt I., Brostoff J. and Male D. Immunology, 6th ed. Mosby, 2001
- Tannock I. and Hill. R.P. The basic science of oncology, 3rd ed. McGraw-Hill, 1998
For all other B.Tech BT 6th sem syllabus go to Anna University B.Tech BIOTECHNOLOGY 6th Sem Course Structure for (R13) Batch. All details and yearly new syllabus will be updated here time to time. Subscribe, like us on facebook and follow us on google plus for all updates.
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