Advanced Biochemistry Syllabus for B.Tech Fifth sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.
The detailed syllabus for Advanced Biochemistry B.Tech 2016-2017 (R13) fifthsem is as follows
OBJECTIVES:
- To orient towards the application of knowledge acquired in solving clinical problems.
- To provide a base for molecular modelling and drug designing
UNIT I : METABOLISM OF AMINO ACIDS [10 Hours]
Biosynthesis of Gly, Ser and Cys; Biosynthesis of six essential amino acids (Met, Thr, Lys, Ile, Val, Leu) and regulation of branched chain amino acids (concerted inhibition, allosteric regulation and enzyme multiplicity, sequential feed back) from oxaloacetate and pyruvate;Biosynthesis of aromatic amino acids. Metabolic disorders associated with branched chain and aromatic amino acid degradation. Important molecules derived from amino acids (auxins, DOPA, Serotonin, porphyrins, T3, T4, Adrenaline, Noradrenaline, histamine, GABA, polyamines etc)
UNIT II : PROTEIN TRANSPORT AND DEGRADATION [5 Hours]
Protein targeting, signal sequence, secretion; Folding, Chaperons and targeting of
organelle proteins, Protein degradation, receptor-mediated endocytosis, turnover.
UNIT III : METABOLISM OF NUCLEIC ACIDS, POLYSACCHARIDES AND
LIPIDS [12 Hours]
Biosynthesis of nucleotides, denovo and salvage pathways for purines and pyrimidines, regulatory mechanisms: Degradation of nucleic acid by exo and endo nucleases. Biosynthesis and degradation of starch and glycogen. Triacylglycerol and phospholipid biosynthesis and degradation; Cholesterol biosynthesis and regulation and targets and action of cholesterol lowering drugs.
[TOTAL : 45 PERIODS]
OUTCOMES: Upon completion of advanced biochemistry, students will be able
- To recognize how fundamental chemical principles and reactions are utilized in
biochemical Processes. - To apply knowledge gained in food and drug industries.
- To define various metabolic concepts for applying them to solve clinical problems.
- To summarize the knowledge of biomolecules to use them in biotechnology industry
TEXT BOOKS:
- Nelson, D.L et al., “Lehninger’s Principles of Biochemistry”
- Stryer, Lubert. “Biochemistry”. 4th Edition, W.H Freeman & Co., 2000.
- Voet, D.J and J.G. Voet and C.W. Pratt “Principles of Biochemistry” 3rd Edition,
John Wiley & Sons Inc., 2008. - Murray, R.K., et al., “Harper’s Illustrated Biochemistry”. 27th Edition. McGraw-Hill, 2006.
REFERENCES:
- Creighton. T.E., “Proteins: Structure and Molecular Properties” 2nd
Edition, W.H.Freeman and Co.,1993. - Salway, J.G., “Metabolism at a Glance”. 2nd Edition, Blackwell Science Ltd., 2000.
For all other B.Tech BT 5th sem syllabus go to Anna University B.Tech BIOTECHNOLOGY 5th Sem Course Structure for (R13) Batch. All details and yearly new syllabus will be updated here time to time. Subscribe, like us on facebook and follow us on google plus for all updates.
Do share with friends and in case of questions please feel free drop a comment.