AP ECET 2020 is a Common Entrance Test for Diploma Holders and for B.Sc.(with Mathematics as one of the optional subjects) to get admission into B.Tech & Pharmacy. APECET 2020 will be conducted by JNTUA on behalf of the Andhra Pradesh State Council of Higher Education for the academic year 2020-2021
The submission of online applications for ECET Andhra Pradesh started on February 2020
AP ECET 2020 Syllabus for Diploma Holders in Engineering, Diploma Holders in Pharmacy and B.Sc.(Mathematics) Graduates.
AP ECET 2020 Exam will be on 30th April 2020 (Thursday)
AP ECET 2020 Syllabus For Section II : Pharmacy Pharmaceutical Chemistry
AP ECET 2020 Syllabus in diploma holders in engineering, diploma holders in pharmacy, B.Sc.(Mathematics) graduates, Common Subjects given in detail.
Section II : Pharmacy Pharmaceutical Chemistry Syllabus
Section- II PHARMACEUTICAL CHEMISTRY
A. Pharmaceutical Chemistry – I ——— 20 Questions
B. Pharmaceutical Chemistry – II ——— 15 Questions
C. Bio-chemistry and Clinical Pathology ——— 15 Questions
1. General discussions on the following inorganic compounds including important physical and chemical properties, medical and pharmaceutical uses, storage conditions and chemical incompatibility.
(A)Acids, bases and buffers Boric Acid, Hydrochloric acid, strong ammonium hydroxide. Calcium hydroxide. Sodium hydroxide and official buffers.
(B) Antioxidants – Hypo phosphorous acid, Sulphur dixide, Sodium bisulphate, Sodium metabisulphite, Nitrogen and Sodium Nitrite.
(C) Gastrointestinal agents:- I. Acidifying agents Dilute hydrochloric acid.
II. Antacids-sodium bicarbontate, Aluminium hydroxide gel, Aluminium phosphate, Calcium carbonate, Magnesium carbonate, Magnesium trisilicate, Magnesium Oxide, Combinations of antacid preparations
III. Protectives and Adsorbents-Bismuth subcarbonate and Kaolin. IV. Saline Cathartics-Sodium Patassium tartate and Magnesium sulphate. (D)Topical Agents:-
I. Protectives-Talc, Zinc Oxide Calamine, Zinc stearate , Titanium dioxide, silicone polymers.
II. Antimicrobials and Astringents-Hydrogen peroxide, Potassium permagnate, Chlorinated lime, Iodine, Solutions of Iodine, PovidoneIodine, Boric acid, Borax, Silver nitrate, Mild silver proein, Mercury, Yellow mercuric oxice, Ammoniated mercury.
III. Sulphur and its compounds-Sublimed sulphur precipitated sulphur, seleniumsulphide.
IV. Astringents:- Alum and Zinc Sulphate. (E) Dental Products-Sodium Flouride, Stannous Flouride, Calcium carbonate, Sodium metaphosphate, Dicalcium phosphate, Strontium chloride, Zinc chloride. (F) Inhalants-Oxygen, Carbon dioxide, Nitrous oxide. (G)Respiratory stimulants-Ammonium carbonate (H)Expectorants and emetics – Ammonium chloride, potassium lodide, Antimony potassium tartrate. (I) Antidotes-Sodium nitrate
2. Major intra and Extcracellular electrolytes:-
(A)Electrolytes used for replacement the rapy-Sodium chloride and its preparation. Potassium chloride and its preparation.
(B) Physiological acid-base balance and electrolytes used-Sodium acetate, Patassium acetate, Sodium bicarbonate injection, Ammonium chloride and its injection.
(C)Combination of oral electrolyte Powder and Solutions.
3. Inorganic Official compounds of iron, Iodine, and Calcium Ferrous Sulphate and Calcium gluconate.
4. Radio pharmaceuticals and Contrast media-Radio activity-Alpha, Beta and Gamma Radiations, Biological effects and Radiations Measurements of radio activity, G.M Counter Radio isotopes their uses, storage and precautions with special reference to the official preparations.
5. Quality control of Drugs and Pharmaceuticals-Importance of quality control, significance efforts, methods used for quality control, sources of impurities in pharmeceuticals. Limit tests for Arsenic Chloride, sulphate, Iron and Heavy Metals.
6. Identification tests for cations and anions as per Indian pharmacopeia.
PHARMACEUTICAL CHEMISTRY – II
- Introduction to the nomenclature of organic chemical systems with particular reference to heterocyclic system containing upto 3 rings.
- The Chemistry of following Pharmaceutical organic compounds. Covering their nomenclature, chemical structure, uses and the important Physical and Chemical Properties. (Chemical structure of on those compounds marked with asterisk. (*) The stability and storage conditions and the different type of Pharmaceutical formulations of these drugs and their popular brand names. Antiseptics and Disinfectants – Proflavine * Benzal – koniumchloride, cetrimide, chlorocresol * Chloroxylene, Formaldehyde solution, Hexachlorophene, Liquified phenol, Nitrofurantoin Sulfonamides – Sulfadiazine Sulfaguandine* Phthalylsulfathiazole, Succinylsulfathizole. Sulfadimethoxazole, Cotrimoxazole, Sulfacetamide* Antileprotic Drugs – Clofazime, Thaimbutosine, Dapsone* Solapsone. Anti – tubercular Drugs – Isoniazed * PAS*, Streptomycin, Rifampicin, Ethambutol* Thiacetazone, Ethionamide, Cycloserine, Pyrazinamide*. Antiamoebic and Anthelmintic Drugs –Emetine, Metronidazole* Halogenated hydroxyquinolines, diloxanidefuroate, paramomycin Piperzine* Mebandazole, D.E.C..* Antibiotics – Benzyl Pencillin*, Phenoxy methyl Pencillin*, Benzathine Pencillin, Ampicillin*, Cloaxocillin, Carbencillin, Gentamicin, Neomycin, Erythromycin, Tetracycline, Cephalexin, Cephaloridine, Cephalothin, Griseofuivin, Chloramphenical. Antifungal agents – Undecylenic acid, Tolnaftate, Nystain, Ampthotericin Hamycin Antimalarial Drugs – Chloroquine, Amodiaquine, Primaquine, Triflu Perazine, Thiothixene, Haloperidol. Triperidol, Oxypertine, Chlordiazepoxide, Diazepam, Lorazepam, Meprobamate. Hypnotics:- Phenobarbitone, butobarbitone, Cyclobarbitone, Nitrazepam, Gluthethimide*, Methypylone, Paraldelnyde, Triclofos sodium, General Anaesthetics – Halothane*, Cyclopropane*, Diethlehter*, Methohexital sodium, Thiopental sodium Trichloroethylene. Antidepressant Drugs -Amitriptyline, imipramine* pheneizine, Tranylcypromine. Analeptics-Theophyline, Caffeine*, Coramine*, Coramine*, Dextroamphetamine Adrenergic Drugs- Adrenaline*, Noradrenaline, Isoprenaline*, Phenylephrine, Salbutamol, Terbutaline, Ephedrine*, Pseudoephedrine. Adrenergic Antagonist – Tolazoline, Propranolol*, Practolol. Cholinergic Drugs-Neostigmine*, Pyridostigmine, Pralidoxime, Pilocarpine, Physostigmine*. Cholinergic antagonists-Atropine*, Hysocine, Homatropine, Propantheline*, Benztropine, Tropicamide, Biperiden*, Diuretic Drugs- Furosemide*, Chlorothiazide, Hydrochlorothiazide*, Benzthiazide, Urea*, Mannitol*, Ethacrynic Acid. Cardiovascular Drugs- Ethyl nitrite*, Glyceryl Trinitrate, Alpha methyldopa, Guanthidine, Chlorpropamide*, Tolbutamide, Glibencalmide, Phenformine*, Metformin. Coagulants and Anti-Coagulants-Heparin, Thrombin, Menadione,*, Bishydroxycoumarin, warfarion sodium. Local Anesthetics lignocaine procaine,Benzocaine Histamine And – histaminic Agents – Histamine, Diphenhydramine*, Promethzine Cyproheptadine, Mepyramine, Pheniramine, Chlorpheniramine*. Analgesics and Anti-pyretics-Morphin, Pethidine*, Codeine, Methadone, Aspirin*, Paracetamol*, Analgin, Dextropropoxyphene. Pentazocine. Non-steroidal anti –inflammatory Agents-indomethacin*, Phenyl butazone oxyphenbutezone lbuprofen Thyroxineand Antithyroids-Thyroxine, Methimazole Methylthiouracil, Propylthiouracil Diagnostic Agensts-lopanoic Acid, Propyliodone Sulfobromophthalein, Sodium indigotindisulfonatae, indigo Carmine, Evansblue, Congo Red Fluorescein Sodiom. *Anticonvulsants, cardiac glycosides antiarrhythmic antihypertensives & vitamins. Steroidal drugs –Betamethazone, Cortisone, Hydrocortisone Prednisolone, Progesterone, Testosterone, Oestardiol, Nandrolone Anti-Neoplasic Drugs-Actinomycines, Azathioprine, Busulphan, Chloarambucil. Cisplatin Cyclophosphamide, Dau norubiein, hydrochloride Flurouracil, Meracaptopurine, Methotrexate, Mytomycin,
BIO-CHEMISTRY AND CLINICAL PATHOLOGY
- Introduction to biochemistry.
- Brief chemistry and role of proteins, polypeptides and amino acids, classifications, Quantitative tests, Biological value, Deficiency diseases.
- Brief Chemistry and role of carbohydrates, Classification qualitative tests, Diseases related to carbohydrate metabolism.
- Brief Chemistry and role of Lipids, Classification, Qualitative tests, Diseases related tolipid metabolism.
- Brief Chemistry and role of vitamins and Coenzymes.
- Role of minerals and water in life processes
- Enzymes; Brief concept of enzymic action. Factors affecting it. Therapeutic and pharmaceutical importance.
- Brief concept of normal and abnormal metabolism of proteins, carbohydrates and lipids.
- Introduction to pathology of blood and urine.
(a) Lymphocytes and Platelets, their role in health and disease.
(b) Erythrocytes Abnormal cells and their significance.
(c) Abnormal constituents of urine and their significance in diseases.
MODEL QUESTIONS FOR PHARMACY
Ball mill works on the principle of
1) Impact
2) Attrition
3) Crushing
4) Compactin
B.C.G. Vaccine contains
1) Living culture
2) Non-living culture
3) Natural culture
4) Artificial culture
Acacia is not used as
1) Diluent
2) Suspending agent
3) Emulsifying agent
4) Binder
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