JNTUH M.Pharm 2017-2018 (R17) Detailed Syllabus Pharmaceutical Formulation Technology

Pharmaceutical Formulation Technology Detailed Syllabus for Pharmaceutical Analysis & Quality Assurance / Quality Assurance M.Pharm first year first sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.

The detailed syllabus for Pharmaceutical Formulation Technology M.Pharm 2017-2018 (R17) first year first sem is as follows.

M.Pharm. I Year I Sem.

Course Objectives: Students will know the preformulation studies, methodology, different excipients used in solid dosage forms and their evaluation with references to production technologies. The students also know the optimization techniques and their applications in pharmaceutical industries.

Course Outcome: Students shall explain the preformulation parameters, apply ICH guidelines and evaluate drug, drug excipients compatibility. Students also explain about formulation and development, use of excipients in tablets, powders, capsules, micro-encapsules and coating techniques. They also learn and apply the statistical design in different formulations.

Unit – I:

1. Preformulation: Goals of preformulation, solid state manipulation and characterization. pH dependent solubility of drug, equilibrium solubility, intrinsic dissolution of drug, particle size distribution.
2. Flow of Powders: Physical properties and importance. Angle of repose, Cars index, compressibility, bulk density, tapped density.

Unit – II: Excipients used in various dosage forms like tablets, capsules, emulsions, suspensions, semisolids and sterile products. Knowledge of packing materials. Drug- excipient compatibility- Drug stability, factors affecting stability, stabilization methods.

Unit – III:

1. Tablets: Types of tablets, granulation methods, highlighting operations such as mixing, drying, milling, blending, lubrication and compression.
2. Tablet coating: Types of coating, steps involved in coating process- pan coating and fluid bed coating and problems associated with coating.
3. Hard Gelatin Capsules: General principles and steps involved in the production of drug loaded hard gelatin capsules, filling operation, filling of powders, granules and pellets.

Unit – IV: Dissolution: Principles of dissolution, factors influencing dissolution, official methods and apparatus. Dissolution of immediate release, controlled release and delayed release products.

Unit – V: Stability testing: Chemical degradation and preventive measures. Various stability testing conditions and use of stabilizers in packing

TEXT BOOKS:

1. Pharmaceutics – The Science of Dosage form design by ME Aulton.
2. Pharmaceutical Dosage forms – Tablets (Vol I, II and III) by Lieberman, Lachman and Schwartz.
3. Pharmaceutical Dosage forms – Capsules (Vol I, II and III) by Avis, Lieberman and Lachman.
4. Pharmaceutical Dosage forms – Disperse systems (Vol I, II and III) by Avis, Lieberman and Lachman.
5. Modern Pharmaceutics by Gilbert S. Banker and Christopher T. Rhodes.
6. Pharmaceutical statistics by Bolton
7. Industrial Pharmacy – Selected Topics , CVS Subramanyam and J Thimmasetty, Vallabha Prakashan Delhi – 2013

REFERENCE BOOKS:

1. The Theory and Practice of industrial Pharmacy by Leon Lachman, Herbert A. Lieberman.
2. Remington’s Science and Practice of Pharmacy by A. Gennaro.
3. Ansel’s Pharmaceutical Dosage form and Drug delivery system by Loyd V. Allen, Jr. Nicholas G. Popovich, Howard C. Ansel.
4. Generic Drug Product Development by Leon Shargel and Isadore Kanfer.
5. Dispensing for Pharmaceutical Students by SJ Carter.

For all other M.Pharm 1st Year 1st Sem syllabus go to JNTUH M.Pharm Pharmaceutical Analysis & Quality Assurance / Quality Assurance 1st Year 1st Sem Course Structure for (R17) Batch.

All details and yearly new syllabus will be updated here time to time. Subscribe, like us on facebook and follow us on google plus for all updates.

Do share with friends and in case of questions please feel free drop a comment.