Advanced Organic Chemistry Lab-I Detailed Syllabus for Pharmaceutical Chemistry M.Pharm first year first sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.
The detailed syllabus for Advanced Organic Chemistry Lab-I M.Pharm 2017-2018 (R17) first year first sem is as follows.
M.Pharm. I Year I Sem.
List of Experiments: (Minimum of 10 experiments shall be conducted)
- Synthesis and characterization of the following drugs:
- Benzanilide by Beckmann rearrangement
- 4-Benzylidene-2-methyloxazol-5-one (or) azalactone
- N-(m-Nitrobenzyl) aniline from m-nitrobenzaldehyde
- 2, 3-Diphenyl quinoxaline
- 1H-Indole-3-carboxaldehyde
- 3, 4-Dihydropyrimidin-2(1H)-one from benzaldehyde, ethyl acetoacetate and urea in presnce of CaCl2 (catalyst).
- Schiff base by microwave irradiation
- Cinnamic acid by Perkin reaction
- β-Ddimethylaminopropiophenone hydrochloride (Mannich base)
- 2-Phenyl indole
- Dimedone (5,5-dimethyl cyclohexane-1,3-dione)
- 3-Bromo cyclohexene from cyclohexene using NBS.
- p-Amino benzyl alcohol from p-amino benzaldehyde using sodium borohydride.
- Cyclohexane-2,5-dicarboxylic acid from benzoic acid (hydrogenation).
- Any other relevant experiments based on theory.
REFERENCES:
- Roth HJ, Kleemann A. Pharmaceutical Chemistry. Vol-I. Drug synthesis. New York: Ellis Horwood Limited; 1988.
- Mann FG, Saunders BC. Practical organic chemistry. 4th ed. New Delhi: Orient Longman; 2005.
- Furniss BS, Hanaford AJ, Smith PWG, Tatchell AR. Vogel’s textbook of practical organic chemistry. 5th ed. Singapore: Longman Singapore Publishers P Ltd; 1989.
- Vogel A. Elementary practical organic chemistry. Part 1: Small scale preparations. 2nd ed. New Delhi: CBS publishers and distributors; 2004.
- Bansal RK. Laboratory manual of organic chemistry. 4th ed. New Delhi: New Age International (P) limited; 2005.
- Kar A. Advanced Practical Medicinal Chemistry. New Delhi: New Age International (P) limited; 2006.
For all other M.Pharm 1st Year 1st Sem syllabus go to JNTUH M.Pharm Pharmaceutical Chemistry 1st Year 1st Sem Course Structure for (R17) Batch.
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