Physical Pharmacy – I Detailed Syllabus for B.Tech first year second sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.
The detailed syllabus for Physical Pharmacy – I B.Tech 2016-2017 (R16) first year second sem is as follows.
B.Tech. I Year II Sem. L T/P/C
Course Code: PS203 4 1/0/4
Course Objectives:
The student shall know important physical properties of drug molecules, phase value & its importance. Different law of thermodynamics, electrolyte and nonelectrolyte solutions, importance of pH and drug research.
Course Outcome:
Student will know about physical properties of molecules, three laws of thermodynamics, properties of electrolytes and non electrolytes, pH and buffers. They also understand the importance of these studies in the physical pharmaceutics & Formulation development.
UNIT – I Physical properties of Drug Molecules: Dielectric constant induced polarization, dipole moment, refractive index and molar refraction and optical rotatory dispersion.
UNIT – II a. Phase equilibria and the phase rule:– System containing single component, System containing two component, two component system containing solid and liquid phases, three component systems b. Thermodynamics: The first law of thermodynamics. The second law of thermodynamics. The third law of thermodynamics, Free energy functions and applications.
UNIT – III a. Solutions of Electrolytes: Properties of solutions of electrolytes. The Arrhenius theory of electrolyte dissociation. The modern theory of strong electrolytes and other coefficients for expressing colligative properties. b. Solutions of Non electrolytes: Concentration expressions, ideal and real solutions, colligative properties, molecular weight determinations.
TEXT BOOKS:
- Patrick J. Sinko, Martin’s Physical Pharmacy and Pharmaceutical Sciences Fifth Edition.
- C. V. S. Subramanyam, Essentials of Physical Pharmacy, Vallabh Prakashan.
- Lippincott Williams and Wilkins, Remington Pharmaceutical Sciences.
REFERENCES:
- Pharmacopoeias, (I.P., B.P., U.S.P. and European.)
- Martindale, The Extra Pharmacopoeia; latest edition, the Royal Pharmaceutical Society.
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