JNTUH B.Tech 2016-2017 (R16) Detailed Syllabus Pharmaceutical lnorganic Chemistry

Pharmaceutical lnorganic Chemistry Detailed Syllabus for B.Tech first year second sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.

The detailed syllabus for Pharmaceutical lnorganic Chemistry B.Tech 2016-2017 (R16)  first year second sem is as follows.

B.Tech. I Year II Sem. L T/P/D C
Course Code: BS201      3 /1/0 3
Prerequisites: Foundation course (No prerequisites)

Course Objectives:

The subject has been designed to make the students understand different categories of inorganic drugs/ compounds which are used as medicinal agents

Course Outcome:

The knowledge gained by the student after studying the subject in detailed manner will be applicable to study and understand the concepts for higher classes.

UNIT – I

1. Classification of Inorganic Pharmaceuticals based on their applications and therapeutic uses.
2. Sources of impurities in pharmaceutical substances.
3. Test for purity a) Setting property of plaster of paris b) Ammonium compounds in sodium bicarbonate c) Oxalate in sodium citrate. d) Barium and thiocynate in Ammonium chloride
4. Qualitative tests for anion and cations
5. Limit tests for arsenic, heavy metals, lead, iron, chloride and sulphate.

Note: Definition, Preparation, Assay principle, Limit tests and Uses of the compounds mentioned in Unit II to Unit V

UNIT – II

1. Electrolytes: a) Sodium and Potassium replenishers: Sodium chloride, compound sodium chloride solution (Ringer solution), potassium chloride, ORS. b) Calcium replenishers: Calcium gluconate, dibasic calcium phosphate, calcium chloride.
2. Acid base regulators: Sodium bicarbonate, sodium lactate, sodium citrate/potassium citrate, sodium acetate, and ammonium chloride
3. Dialysis fluids: Haemodialysis fluids.

UNIT – III Gastro-intestinal agents.

1. Acidifiers and Antacids: Dilute hydrochloric acid, sodium acid phosphate, sodium bicarbonate, aluminium hydroxide gel, dried aluminium hydroxide gel, magnesium oxide (Magnesia), magnesium hydroxide mixture, magnesium trisilicate.
2. Adsorbents and related drugs: Light kaolin, heavy kaolin, and activated charcoal.
3. Laxatives: Magnesium sulphate, sodium phosphate.
4. Mineral Nutrients / Supplements a) Haematinics – Ferrous sulphate, ferrous fumarate, ferrous gluconate, ferric ammonium citrate, iron and dextrose injection. b) Halogens: Iodine, Iodides.
5. Pharmaceutical aids: a) Excipients: Dicalcium phosphate, magnesium stearate, talc and calcium carbonate (Precipitated chalk). b) Suspending agents: Bentonite, colloidal silica. c) Colorants: Titanium oxide, Ferric oxide

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TEXT BOOKS

• A. H. Beckett and J. B. Stenlake, Practical pharmaceutical chemistry, Part-I. The Athtone press,
• University of London, London.
• P. Gundu Rao, Inorganic pharmaceutical chemistry; Vallabh Prakashan, Delhi.
• Advanced Inorganic Chemistry by Satya Prakash, G. D. Tuli

REFERENCES

• L.M. Atherden, Bentley and Driver’s Textbook of Pharmaceutical Chemistry Oxford University Press, London.
• Indian Pharmacopoeia 1996, 2006

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