Clinical & Pharmaceutical Biotechnology detail syllabus for Biotechnology (Bt), 2017 scheme is taken from VTU official website and presented for VTU students. The course code (17BT81), and for exam duration, Teaching Hr/week, Practical Hr/week, Total Marks, internal marks, theory marks, duration and credits do visit complete sem subjects post given below.
For all other bt 8th sem syllabus for be 2017 scheme vtu you can visit BT 8th Sem syllabus for BE 2017 Scheme VTU Subjects. The detail syllabus for clinical & pharmaceutical biotechnology is as follows.
Course Objectives:
The objective of this course is to educate students about drug design, formulation; importance of pharmacokinetics & pharmacodynamics study. To list the applications & advantages of Pharmaceutical & Clinical Biotechnology
Module 1
For complete syllabus and results, class timetable and more pls download iStudy. Its a light weight, easy to use, no images, no pdfs platform to make students life easier.
Module 2
PHARMACOKINETICS AND PHARMACODYNAMICS: Pharmacodynamics and Pharmacokinetics of protein based drugs. Disease target identification and selection, receptor-based approaches, agonists, antagonists, enzyme inhibitors Basic concepts, ADME definitions, Need of pharmacokinetic study; Interpretations from pharmacokinetics parameters, Examples of Pharmacodynamic parameters of various drugs; Evolution of Drug Metabolism Phase I Metabolism (microsomal oxidation, hydroxylation, dealkylation) Phase II Metabolism (Drug conjugation pathway) CYP Families.
Module 3
PHARMACOTHERAPY Classification of drugs based on therapeutic actions using suitable examples Special emphasis on Vitamins, cold remedies, laxatives, analgesics, non-steroidal contraceptives, external antiseptics, antacids, antibiotics, biologicals, herbal products. Pharmacotherapy of migraine, cancer, TB, diabetes and male sexual dysfuntion. Hormone replacement therapy.
Module 4
For complete syllabus and results, class timetable and more pls download iStudy. Its a light weight, easy to use, no images, no pdfs platform to make students life easier.
Module 5
CLINICAL RESEARCH:
The philosophy behind and organization of clinical research. Pre-clinical development to support testing in humans: In vitro and in vivo testing of new compounds, Relationship between animal and human pharmacology. Safety testing – acute, sub acute toxicology, immunotoxicology, Concepts of pharmacovigilance, General principles and guide to data sources, types of epidemiology study designs, ecological (correlation) studies, case reports, prevalence surveys or cross-sectional studies, case control studies, Clinical trials-informed consent, Placebo Responses, Clinical Registries. Clinical Research Institutes, Data Management, Clinical Research from Pharmaceutical Industry.
Course Outcomes:
After studying this course, students will be able to:
- Explain the significance of pharmaco-kinetic models, pharmaco-dynamic principles, various dosage forms and formulation
- Understand the specific techniques used in biotherapy & clinical Biotechnology
- Comprehend specific applications of pharmaceutical & clinical Biotechnology
Reference Books:
- Basic & Clinical Pharmacology by Bartram G. Katzung, Mc Graw Hill.
- The Theory & Practice of Industrial Pharmacy by Leon Lachman, Herbert A. Lieberman & Joseph & Kanig, Vergese Publishing House Bombay.
- Enzyme Technologies for pharmaceutical and biotechnological applications by Herbert A Kirst, Wu-Kuang Yeh, Milton J. Marcel Dekker Publications.
- Developmental Biology, by Scott F. Gilbert, Wiley Publications.
- Current Trends in Pharmacology by Arunabha Ray & Kavitha Gulati, IK Intl.
- Developmental Biology, Scott F. Gilbert, Cambridge University Press.
- Molecular Biology of the Cell, by Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, James D. Watson, Garland Science.
- Text book of Medical Biochemistry by R L Nath, New Age Publishers.
- Pharmaceutical Biotechnology by K Sambamurthy & Ashutosh Kar, New Age Publishers.
- ICH guideline Q6B, Freelance Publishing.
- Basic & Clinical Pharmacology by Bartram G. Katzung, Mc Graw Hill.
Text Books:
- Biochemistry and Biotechnology by Gary Walsh, John Wiley & Sons Ltd.
- Principles and Practice of Clinical Research by J. I. Gallin and F. P. Ognibene, Elsevier Publication.
- Hematology by William J. Williams, Ernest Beutler, Allan JU. Erslev, Marshall A. Lichtman, IK Publishers.
- Stem Cell Biology by Marshak, Cold Spring Harbour Symposium Pulblications.
- Current Trends in Pharmacology by Arunabha Ray & Kavitha Gulati, IK Intl.
- An Introduction to Synthetic Drugs by Singh & Rangnekar, Himalaya publishing House.
- Biopharmaceuticals, Biochemistry and Biotechnology by Gary Walsh, Wiley Pub.
- Principles of Medicinal Chemistry by Foye, Lippincott Williams & Wilkins Publishers.
- Industrial Pharmaceutical Biotechnology by Heinrich Klefenz, Wiley-VCH edition.
- Biopharmaceutical Drug Design and Development by S Wu-Pong, Y Rojanasakul, and J Robinson.
- Pharmaceutical Biotechnology by K Sambamurthy & Ashutosh Kar, New Age.
- Pharmaceutical Biotechnology by S P Vyas and V K Dixit, CBS Publishers.
For detail syllabus of all other subjects of BE Bt, 2017 scheme do visit Biotech 8th Sem syllabus for 2017 scheme.
Dont forget to download iStudy for latest syllabus and results, class timetable and more.