Clinical Biochemistry detail syllabus for Biotechnology (Bt), 2017 scheme is taken from VTU official website and presented for VTU students. The course code (17BT46), and for exam duration, Teaching Hr/week, Practical Hr/week, Total Marks, internal marks, theory marks, duration and credits do visit complete sem subjects post given below.
For all other bt 4th sem syllabus for be 2017 scheme vtu you can visit BT 4th Sem syllabus for BE 2017 Scheme VTU Subjects. The detail syllabus for clinical biochemistry is as follows.
Course Objectives:
This course will enable students
- Learn the structure and function of metabolic pathways for carbohydrates, amino acids and lipids; their alterations in disorders.
- Gain insight into the clinical manifestations of renal, hepatic, pancreatic, gastric and intestinal functions.
Module 1
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Module 2
INBORN ERRORS OF METABOLISM:
- Disorders of amino acid metabolism – Phenylalanemia, homocystinuria, tyrosinemia, MSUD, phenylketonuria, alkaptonuria, albinism and animoacidurias.
- Disorders of nucleic acid metabolism- Disorders in purine/ pyrimidine metabolism.
Module 3
DISORDERS OF ACID-BASE BALANCE AND THEIR RESPIRATORY AND RENAL MECHANISMS: Evaluation of organ function tests, Assessment and clinical manifestations of renal, hepatic, pancreatic, gastric and intestinal functions. Clinical importance of bilirubin. Diagnostic enzymes: Principles of diagnostic enzymology. Clinical significance of aspartate aminotransferase, alanine aminotransferase, creatine kinase, aldolase and lactate dehydrogenase. Enzyme tests in determination of myocardial infarction. Enzymes of pancreatic origin and biliary tract.
Module 4
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Module 5
BIOCHEMICAL ASPECTS OF HEMATOLOGY: Disorders of erythrocyte metabolism, hemoglobinopathies, thalessemias thrombosis and anemias.
Laboratory tests to measure coagulation and thrombolysis. Detoxification in the body: enzymes of detoxification, polymorphism in drug metabolizing enzymes. Mechanism of drug action and channels of its excretion, Disorders of vitamins and trace elements..
Course Outcomes:
After studying this course, students will be able to:
- Discuss the biochemistry and pathophysiology associated with various disorders of metabolism and inborn errors of metabolism.
- Describe the structure and function of metabolic pathways for carbohydrates, amino acids and lipids.
- Explain the medical problems associated with abnormal lipoprotein levels and therapeutic agents used to treat lipid disorders.
- Assess the clinical manifestations of renal, hepatic, pancreatic, gastric and intestinal functions.
Reference Books:
- Review of Medical Physiology (Lange Basic Science) (Paperback) By William F. Ganong. Publisher: McGraw-Hill Medical
- Harper’s Biochemistry (Lange Medical Books) (Paperback) By Robert K. Murray, Daryl K. Granner, Peter A. Mayes and Victor W. Rodwell. Publisher: Appelton and Lange.
- Clinical Biochemistry by Richard Luxton. Scion Publishing Ltd.
- Clinical Biochemistry Paperbackby Nanda Maheshwari, 2008.
- Appreciate the biochemical aspects of hematology.
Text Books:
- Textbook of Medical Biochemistry by MN Chatterjea and Rana Shinde, Jaypee Brothers.
- Lehninger- Principles of Biochemistry by David L. Nelson and Michael M. Cox, 5th Edition, WH Freeman and Company.
- Medical Biochemistry (Paperback) By John W. Baynes and Marek Dominiczak. Publisher: Mosby.
- Clinical Biochemistry: 3rd Ed By Allan Gaw, Michael Murphy, Robert Cowan, Denis O’Reilly, Michael Stewart and James Shepherd. Publisher: Churchill Livingstone.
For detail syllabus of all other subjects of BE Bt, 2017 scheme do visit Bt 4th Sem syllabus for 2017 scheme.
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