Biomolecular Engineering BT 6th Sem Syllabus for VTU BE 2017 Scheme (Professional Elective-2)

Biomolecular Engineering detail syllabus for Biotechnology (BT), 2017 scheme is taken from VTU official website and presented for VTU students. The course code (17BT651), and for exam duration, Teaching Hr/week, Practical Hr/week, Total Marks, internal marks, theory marks, duration and credits do visit complete sem subjects post given below.

For all other bt 6th sem syllabus for be 2017 scheme vtu you can visit Biotech 6th Sem syllabus for BE 2017 Scheme VTU Subjects. For all other Professional Elective-2 subjects do refer to Professional Elective-2. The detail syllabus for biomolecular engineering is as follows.

Course Objectives:

This course will enable students

1. To learn the energetics of biological systems.
2. To understand the kinetics of enzymes, thermodynamics of biomolecular interactions and the applications of bioengineering.

Module 1

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Module 2

ENZYMES KINETICS: Enzymes as Biological Catalysts, Enzyme Activation, Unireactant Enzymes, Multi-site and Allosteric Enzymes, Simple Inhibition, Multiple Inhibition Models, Multi-Reactant Systems, pH and Temperature Effects. Reaction kinetics and enzyme energetics for the case of Catalytic Antibodies.

Module 3

BIOENERGETICS: Energetics of Biological Systems, Molecular Recognition. Concepts of Free Energy, Enthalpy and Entropy in the living cell, Biochemical Reactions, Metabolic Cycles, ATP Synthesis (Respiration and Photosynthesis), Membrane Ion Gradients (ATP and Ion Gradients), Protein Folding, Protein-Nucleic Acid interactions. Rheology of DNA. Protein misfolding and disease.

Module 4

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Module 5

APPLICATIONS :
Biodegradable materials, Polymeric scaffolds for tissue engineering applications. Biopolymers: heparin and heparin-like polysaccharides, proteoglycans, chemically modified glycosaminoglycans. Design and production of biomaterials as biosensors. Nanoscale biosensors. Case studies: Engineered T-Cell Therapeutics, Vaccines.

Course Outcomes:

After studying this course, students will be able to:

• Define bioenergetics.
• Explain the kinetics of enzymes, thermodynamics of biomolecular interactions and the applications of bioengineering.

Reference Books:

1. Biocatalyst for Industry by J.S. Dordrick, Plenum press, New York.
2. Enzymes in Industry: Production and Applications by W. Gerhartz VCH Publishers.
3. Fundaments of Enzymology by Prices and Stevens, Oxford Press.

Text Books:

1. Molecular Cell Biology by H. Lodisch et al, W.H.Freeman and Co.
2. Enzyme Kinetics by I.H.Segal, Wiley Interscience.
3. Comphrehensive Enzyme Kinetics by V. Leskovac, Kluwer Academic/Plenum Publishers.
4. Thermodynamics and Kinetics For the Biological Sciences By G.G. Hammes, Wiley Interscience.
5. Enzymes – Biochemistry, Biotechnology, Clinical Chemistry by Trevor Palmer, Horwood Publishing Limited.
6. Enzyme Technology by M.F. Chaplin and C. Bucke, Cambridge Press.

For detail syllabus of all other subjects of BE Biotech, 2017 regulation do visit Biotech 6th Sem syllabus for 2017 Regulation.

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