Biochemical Engineering [D.C] CHE 7th Sem Syllabus for VTU BE 2017 Scheme

Biochemical Engineering [D.C] detail syllabus for Chemical Engineering (Che), 2017 scheme is taken from VTU official website and presented for VTU students. The course code (17CH71), and for exam duration, Teaching Hr/week, Practical Hr/week, Total Marks, internal marks, theory marks, duration and credits do visit complete sem subjects post given below.

For all other che 7th sem syllabus for be 2017 scheme vtu you can visit CHE 7th Sem syllabus for BE 2017 Scheme VTU Subjects. The detail syllabus for biochemical engineering [d.c] is as follows.

Course Objectives:

To enhance skills in the areas of biochemical processes to provide the fundamental background of biological systems, biomolecules, micro-organisms, fermentation processes, Bioreactors and kinetics.

Module 1

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Module 2

Biochemistry: Chemicals of Life: Lipids, Sugars, Polysaccharides, Amino acids. Vitamins, Biopolymers, Nucleic Acids: RNA, DNA and their derivatives (Structure, Biological function and Importance for life only to be studied). Enzymes and Proteins: Detailed structure of proteins and enzymes. Functions. Methods of Production and purification of Enzymes. Nomenclature and Classification of enzymes. Kinetics and
mechanism of Enzyme action: Michaelis-Menten, Briggs-Haldane approach. Derivation.

Module 3

Kinetics of Enzyme Action: Reversible Enzyme. Two-substrate. Multi-complexes enzyme kinetics (Derivation of rate equations). Experimental determination of rate parameters: Batch and continuous flow experiments. Line weaver-Burk, Eadie-Hofstee and Hanes-Woolf Plots. Batch Kinetics (Integral and Differential methods). Enzyme Inhibition: Effect of Inhibitors (Competitive, noncompetitive, uncompetitive, substrate and product inhibitions), Temperature and pH on the rates enzyme catalyzed reactions. Determination of kinetic parameters for various types of inhibitions. Dixon method. Enzyme immobilization: Uses. Methods of enzyme immobilization.

Module 4

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Module 5

Kinetics of Microorganisms: Transient growth kinetics (Different phases of batch cultivation). Quantification of growth kinetics: Substrate limited growth, Models with growth inhibitors, Logistic equation, Filamentous cell growth model. Continuous culture: Optimum dilution rate and washout condition in Ideal Chemostat. Introduction to Fed-batch reactors. Downstream Processing: Strategies and steps involved in product purification. Methods of cell disruption, Filtration, Centrifugation, Sedimentation, Chromatography, Freeze drying / lyophilization. Membrane separation Technology: Reverse Osmosis, Ultra filtration, Micro filtration, Dialysis.

Course Outcomes:

1. Understanding of biological basics and bioprocessing.
2. Understanding the difference between bioprocesses and chemical processes.
3. Bioprocess design and operation.
4. Bioreactor configuration and choice of bioreactor
5. Heat & mass transfer considerations and scale up of bioprocesses
6. Introduction to bioprocess monitoring/control

Question paper pattern:

• The question paper will have ten questions.
• Each full Question consisting of 20 marks
• There will be 2 full questions(with a maximum of four sub questions) from each module.
• Each full question will have sub questions covering all the topics under a module.
• The students will have to answer 5 full questions, selecting one full question from each module.

Graduate Attributes (as per NBA):

1. Critical thinking
2. Problem solving
3. Use of modern tools
4. Life – long learning
5. Collaborative and multidisciplinary work

Text Books:

1. Biochemical Engineering Fundamentals, Bailey and Ollis, 2nd edn, McGraw Hill, 1976.
2. Bioprocess Engineering, Shuler M. L. and Kargi F., 2 edn, Prentice Hall, 2002.

Reference Books:

1. Biochemical Engineering, James Lee, Prentice Hall, 1992.
2. Biochemical Reactors, Atkinson B, Pion Ltd., London, 1974.
3. Industrial Microbiology, Casida, wiley, New York, 1968
4. Principles of Fermentation Technology, Stanbury and Whitekar, 2nd edn, Butterworth-Heinemann An Imprint of Elsevier

For detail syllabus of all other subjects of BE Che, 2017 scheme do visit Chemical Engineering 7th Sem syllabus for 2017 scheme.

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