Molecular Biology detailed Syllabus for Biotechnology Engineering (BIOTECH), 2018 scheme has been taken from the VTUs official website and presented for the VTU students. For Course Code, Subject Names, Teaching Department, Paper Setting Board, Theory Lectures, Tutorial, Practical/Drawing, Duration in Hours, CIE Marks, Total Marks, Credits and other information do visit full semester subjects post given below. The Syllabus PDF files can also be downloaded from the official website of the university.
For all other VTU BIOTECH 4th Sem Syllabus for BE 2018 Scheme, do visit VTU BIOTECH 4th Sem Syllabus for BE 2018 Scheme Subjects. The detailed Syllabus for molecular biology is as follows.
Course Objectives:
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Module 1
INTRODUCTION & REPLICATION OF DNA: Chromosomal theory of heredity, genes and their location. Genetic code, Information flow in biological systems: central dogma, updated central dogma. Structures and forms of nucleic acids-DNA and RNA. Reversible denaturation and hyperchromic effect. Tertiary structure of DNA: DNA supercoiling. Replication of DNA, structure and function of DNA polymerases, models of replications in prokaryotes, mechanism of DNA replication and enzymes involved. Proteomics of DNA replication, Fidelity of DNA replication, Inhibitors of DNA replication
Module 2
TRANSCRIPTION: Structure and function of RNA polymerases (prokaryotes & eukaryotes), mechanism of transcription in prokaryotes and eukaryotes, transcription factors, Fidelity of RNA synthesis, post-transcriptional processing (RNA editing, siRNA, splicing, poly A tail and 5′ capping), Ribozymes, transcription inhibitors.
Module 3
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Module 4
GENE EXPRESSION IN PROKARYOTES & EUKARYOTES: Regulation of gene expression in prokaryotes: Operon model, gal, lac, trp Operons; positive versus negative regulation. Regulation of eukaryotic gene expression, transcriptional control, homeobox in the control of developments in insects and vertebrates.
Module 5
GENETIC RECOMBINATION, MUTATION & GENE MAPPING: Genetic recombination in bacteria and viruses, site specific recombination, transposons and insertion sequences; Retroviruses. DNA damage & Repair, Mutation, Role of recombination and transposition in evolution; gene mapping techniques.
Course Outcomes:
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Question paper pattern:
- The question paper will have ten full questions carrying equal marks.
- Each full question will be for 20 marks.
- There will be two full questions (with a maximum of four sub- questions) from each module.
- Each full question will have sub- question covering all the topics under a module.
- The students will have to answer five full questions, selecting one full question from each module.
Text Books:
- Essentials of Molecular Biology David Freifelder Narosa Pub. House 1990
- Molecular Biology of the Cell Alberts et al Garland Publishing 2002.
- Molecular Biology of the Gene James D Watson et al Pearson Education Seventh Edition 2017
Reference Books:
For the complete Syllabus, results, class timetable, and many other features kindly download the iStudy App
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For detail Syllabus of all other subjects of BE 4th Sem Biotechnology Engineering, visit (BIOTECH) 4th Sem Syllabus Subjects.
For all (CBSE & Non-CBSC) BE results, visit VTU BE all semester results direct links.