Phytochemistry Detailed Syllabus for Pharmacy Practice M.Pharm first year first sem is covered here. This gives the details about credits, number of hours and other details along with reference books for the course.
The detailed syllabus for Phytochemistry M.Pharm 2017-2018 (R17) first year first sem is as follows.
M.Pharm. I Year I Sem
Course Objective: Helps the students to get exposed to natural product drug discovery and to perform quantitative and qualitative evaluation of herbal extracts. To understand the chemistry of important phytoconsitituents of different categories.
Course Outcome: On the basis of chemistry data of phytoconsitituents students will acquire knowledge on various types of phytoconstituents present in the plants.
UNIT – I : Extraction and Phytochemical studies: Recent advances in extractions with emphasis on selection of method and choice of solvent for extraction, successive and exhaustive extraction and Methods of fractionation. Separation of phytoconstituents by latest CCCET, SCFE techniques including prep and Flash column chromatography.
UNIT – II : Sources, Chemical structure, Identification tests, mechanism of action, SAR and uses of following Alkaloids
- Caffeine
- Quinine, Reserpine, Atropine, Vinca alkaloids
- Morphine and brief account on its derivatives and analogues
UNIT – III : Sources, Chemical structure, Identification tests, mechanism of action SAR, uses and semi-synthetic derivatives of the following phytopharmaceuticals: Camptothecin, Podophyllotoxin, Taxol, Digoxinand Artemisinine
UNIT – IV : Structure elucidation of the following compounds by spectroscopic Techniques like UV, IR, NMR (1H, 13C)
- Carvone, Citral, Menthol
- Luteolin, Kaempferol
- Nicotine, Caffeine
UNIT – V : Drug discovery and development: History of herbs as source of drugs and drug discovery. Sourcing and archiving Natural products for discovery. Evaluating natural products for therapeutic properties, identifying the biologically active Natural products, the lead structure selection process and structure development with suitable examples from the following source: artemesin, andrographolides.
RECOMMENDED/ REFERENCE BOOKS:
- Phytochemical methods of chemical analysis by Harbone
- Modern methods of plant analysis- peach & M.V. Tracey Vol. 1 to VII
- Pharmacognosy & Phytochemistry of medical plants by Jean Brunton
- Thin layer chromatography by Stahl
- Chemistry of natural products by Atur Rahman
- Comprehensive Medicinal Chemistry, Vol 1-6, Elsevier Publication
- Medicinal Chemistry Drug Discovery by Donald J, Abrahm,
- Plant drug analysis by Wagner
- Clarke’s isolation & identification of drugs by AC Mottal
- Chromatography of Alkaloids by Varpoorte Swendson
- Jenkins Quantitative pharmaceutical chemistry by AN Kenwell
- Standardization of botanicals by V. Rajpal Vol 1 & 2
- Medicinal chemistry and drug discovery by Burger’s
- Chemistry of Natural Products by S. V. Bhat, B. A. Nagasampagi, M. Sivakumar
- Herbal Drugs: Quality and Chemistry by D. D. Joshi
For all other M.Pharm 1st Year 1st Sem syllabus go to JNTUH M.Pharm Pharmacy Practice 1st Year 1st Sem Course Structure for (R17) Batch.
All details and yearly new syllabus will be updated here time to time. Subscribe, like us on facebook and follow us on google plus for all updates.
Do share with friends and in case of questions please feel free drop a comment.